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Antibodies for Apoptosis
Polyclonal antibodies

Apoptosis, or programmed cell death, is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- and/or caspase recruitment domain (CARD) containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. Apoptosis also occurs during normal cellular differentiation and development of multicellular organisms and is induced by certain cytokines including TNF and Fas ligand of the TNF family through their DD-containing receptors, TNFR1 and Fas. 


Western blot analysis of 50 µg of total cell lysate from HeLa cells with anti-FLIPalpha (CT) at 1:1000 dilution.

Western blot analysis of 50 µg of total cell lysate from HeLa cells with anti-FLIPalpha (CT) at 1:1000 dilution.

Antibodies against many recently identified proteins.
 

For a detailed data sheet as a pdf-file, please click on the product No.
LIST OF ANTIBODIES: ORDER INFORMATION, SHIPPING AND STORAGE
order # product reactive* applic.* description amount
2215PR Anti-Acinus (CP) h. m. WB Inducer of chromatin condensation 100 µg
24170SB Anti-Acinus (CT)** h. WB,IHC Inducer of chromatin condensation 100 µg
2217PR Anti-Acinus (CT)** h. WB Inducer of chromatin condensation 100 µg
2219PR Anti-Acinus (IN) h. WB Inducer of chromatin condensation 100 µg
2241PR Anti-Acinus (NP) h. WB Inducer of chromatin condensation 100 µg
24169SB Anti-Acinus (NT) h. WB,IHC Inducer of chromatin condensation 100 µg
2051PR Anti-ADAM10 (CT) h. WB TNF-alpha converting enzyme 100 µg
2301PR Anti-AIF (CT) h. m. r. WB Apoptosis inducing factor 100 µg
2267PR Anti-AIF (IN) h. m. r. WB Apoptosis inducing factor 100 µg
2239PR Anti-AIF (NT) h. WB Apoptosis inducing factor 100 µg
2015PR Anti-Apaf-1 (CT) h. WB Apoptosis protease activ. factor 100 µg
2013PR Anti-Apaf-1 (NT) h. WB Apoptosis protease activ. factor 100 µg
2223PR Anti-APRIL (ED) h. WB A new member in the TNF family 100 µg
2415PR Anti-APRIL (ED2 h. WB A new member in the TNF family 100 µg
2081PR Anti-ARC (CT) h. WB Apoptosis repressor 100 µg
2185PR Anti-ARC (NT) h. m. r. WB Apoptosis repressor 100 µg
3305PR Anti-ARMER (CT) (ARL6IP, AIPI) h. m. WB An inhibitor of apoptosis 100 µg
3025PR Anti-ARTS h. WB An Apoptosis related protein 100 µg
2287PR Anti-ASC h. WB New CARD-containing adaptor protein 100 µg
1151PR Anti-ASK1 (CT) h. WB MAPK kinase kinase 100 µg
3343PR Anti-Bad (Bcl-2-like 8) h. m. r. WB, IHC Bcl-2 family member 100 µg
2221PR Anti-BAFF (CT) h. m. r. WB B cell activating factor in TNF family 100 µg
3097PR Anti-BAFF-R (CT) h. m. r. WB Receptor for BAFF 100 µg
3347PR Anti-Bak (NT) h. m. WB A member of the bcl-2 family 100 µg
3351PR Anti-Bax (NT) h. WB A member of the bcl-2 family 100 µg
3335PR Anti-Bcl2 (NT) h. m. WB, IHC A member of the bcl-2 family 100 µg
3337PR Anti-Bcl2 (IN) h. WB A member of the bcl-2 family 100 µg
24129SB Anti-Bcl10 (CT) h. WB,IHC Involved in apoptosis 100 µg
2161PR Anti-Bcl10 (NT) h. WB Involved in apoptosis 100 µg
3165PR Anti-Bcl-G (CT) (Bcl-2-like 14) h. m. r. WB Bcl-2 family member 100 µg
3341PR Anti-Bcl-xL h. WB A member of the bcl-2 family 100 µg
24209SB Anti-BCL-G (CT) h. WB,IHC Novel pro-apoptotic member of the BCL-2 family 100 µg
24210SB Anti-BCL-G (NT) h. WB,IHC Novel pro-apoptotic member of the BCL-2 family 100 µg
2397PR Anti-BCMA h. WB Receptor for BAFF and APRIL 100 µg
3353PR Anti-Bid (CT) h. m. WB A member of the bcl-2 family 100 µg
3355PR Anti-Bid (IN) h. m. WB A member of the bcl-2 family 100 µg
2065PR Anti-Bim (IN) h. m. r. WB New member in Bcl-2 family 100 µg
3405PR Anti-BIM (IND2) (BOD) h. m. r. WB An intermediate in the TLR and Bmp signaling pathway 100 µg
3029PR Anti-Bmf (CT) h. WB New member in Bcl-2 family 100 µg
3031PR Anti-Bmf (NT) h. m. WB New member in Bcl-2 family 100 µg
2289PR Anti-Bnip3L (IN) h. WB A new member in Bcl-2 family 100 µg
2011PR Anti-CAD (CT) m. WB Caspase activated DNase 100 µg
2007PR Anti-CAD (I17) m. WB Caspase activated DNase 100 µg
3187PR Anti-CARD8 (Cardinal/TUCAN) h. WB New CARD-containing protein 100 µg
3189PR Anti-CARMA1 h. m. WB Lymphocyte activating CARD-containing protein 100 µg
2515PR Anti-CARD9 h. WB New CARD-containing protein 100 µg
1128PR Anti-Casp-10 (CT) h. m. WB Caspase-activating protease 100 µg
24300SB Anti-Casp-10 (NT) h. WB,IHC Caspase-activating protease 100 µg
2327PR Anti-Casp-12 (IN) h. m. r. WB A new caspase 100 µg
2325PR Anti-Casp-12 (NT) h. m. r. WB A new caspase 100 µg
3197PR Anti-Casp12 (sml) h.m.r. WB A new caspase 100 µg
3195PR Anti-Casp12 (lrg) h.m.r. WB A new caspase 100 µg
2245PR Anti-Casp-13 (CT) h. m. r. WB Evolutionarily related ICE 100 µg
2071PR Anti-Casp-9 (I16) h. WB Caspase-3 activator 100 µg
2073PR Anti-Casp-9 (I20) h. WB Caspase-3 activator 100 µg
3325PR Anti-cIAP (CT) h. m. WB Apoptosis inhibitor protein 100 µg
2085PR Anti-CIDE-A (CT) h. WB Cell death activator 100 µg
24316SB Anti-CIDE-3 h. WB, IHC Cell death activator 100 µg
24264SB Anti-CLAN Protein h. WB,IHC CARD-containing, apoptosis-regulating protein 100 µg
3313PR Anti-DAD1 h.m. WB An inhibitor of apoptosis 100 µg
2323PR Anti-DAPK2 h. m. r. WB Death-associated protein kinase 2 100 µg
1163PR Anti-Daxx (CT) h. m. WB Cell death adapter molecule 100 µg
2179PR Anti-DcR1 (CT) h. WB Decoy receptor 1 for TRAIL 100 µg
2299PR Anti-DcR1 (ED2) h. m. r. WB Decoy receptor for TRAIL 100 µg
2023PR Anti-DcR2 (CT) h. WB Decoy receptor for Trail 100 µg
2021PR Anti-DcR2 (ID) h. WB Decoy receptor for Trail 100 µg
2140PR Anti-DcR3/TR6 h. WB Decoy receptor for FASL & LIGHT 100 µg
2227PR Anti-DEDAF h. m. WB Novel caspase-interacting protein 100 µg
24281SB Anti-DEDD2 h. IHC Involved in the regulation of nuclear events 100 µl
2155PR Anti-DFF40 (IN) h. WB Caspase activated DNase 100 µg
2153PR Anti-DFF40 (NT) h. WB Caspase activated DNase 100 µg
2107PR Anti-DFF40/CAD (I18) m. WB Caspase activated DNase 100 µg
1141PR Anti-DFF45 (CT) h. WB DNA fragmentation factor 100 µg
1148PR Anti-DFF45 (NT) h. WB DNA fragmentation factor 100 µg
24267SB Anti-DIABLO (CT) h. WB,IHC Promotes apoptosis by binding to IAPs 100 µg
2057PR Anti-DNase II (IN) h. WB DNase involved in apoptosis 100 µg
2059PR Anti-DNase ll (CT) h. WB DNase involved in apoptosis 100 µg
1120PR Anti-DR3 (CT) h. WB Cell death receptor 100 µg
1158PR Anti-DR3 (ED) h. WB Cell death receptor 100 µg
1166PR Anti-DR3 (NT) h. WB Cell death receptor 100 µg
1139PR Anti-DR4 (CT) h. WB Death receptor for TRAIL 100 µg
1167PR Anti-DR4 (NT) h. WB Death receptor for Trail 100 µg
2019PR Anti-DR5 (CT) h. m. WB Death receptor for Trail 100 µg
2157PR Anti-DR6 (NT) h. WB Death receptor 6 100 µg
2147PR Anti-DRAK1 (NT) h. WB,IHC Apoptosis inducing kinase 100 µg
2149PR Anti-DRAK2 (CT) h. WB Apoptosis inducing kinase 100 µg
3035PR Anti-EndoG h.m.r. WB Endonuclease G 100 µg
2279PR Anti-F1 alpha (CT) h. m. r. WB Novel death receptor binding protein 100 µg
2271PR Anti-FLASH (CT) h. WB Involved in Fas induced apoptosis 100 µg
24167SB Anti-FLASH (NT) h. WB,IHC Involved in Fas induced apoptosis 100 µg
1159PR Anti-FLIP (NT) h. WB FLICE inhibitory protein 100 µg
1161PR Anti-FLIPa (CT) h. m. WB FLICE inhibitory protein 100 µg
2055PR Anti-FLIPg/d (CT) h. WB FLICE inhibitory protein 100 µg
24272SB Anti-GRIM-19 h. WB,IHC Novel cell death regulatory molecule 100 µg
2003PR Anti-ICAD (CT) m. WB Inhibitor of CAD 100 µg
2001PR Anti-ICAD (NT) m. WB Inhibitor of CAD 100 µg
3107PR Anti-Ipaf (CARD12/CLANA) h. WB ICE protease activating factor 100 µg
24276SB Anti-ILP-1 h. WB,IHC Potent inhibitor of apoptosis 100 µg
3017PR Anti-ILP-2 h.m.r. WB A new member in IAP family 100 µg
3201PR Anti-ILPIP (CT) h. WB An IAP binding protein 100 µg
3199PR Anti-ILPIP (IN) h. m. r. WB An IAP binding protein 100 µg
24207SB Anti-Livin (NT) h. IHC A new member in IAP family 100 µg
2505PR Anti-Livin, KIAP h. WB A new member in IAP family 100 µg
24271SB Anti-MAP-1 h. WB,IHC Modulator of apoptosis 100 µg
2089PR Anti-mCIDE-A (CT) m. WB Cell death activator 100 µg
2091PR Anti-mCIDE-B CT) m. WB Cell death activator 100 µg
1156PR Anti-mFLIP (CT) h. WB FLICE inhibitory protein 100 µg
2411PR Anti-mSmac (CT) h. m. r. WB (DIABLO) IAPs binding protein 100 µg
2237PR Anti-mSurvivin (CT) m. WB New inhibitor of apoptosis 100 µg
3359PR Anti-NADE h. m. WB A novel apoptosis related protein 100 µg
3315PR Anti-NAIP (CT) h. WB Neuronal apoptosis inhibitor protein 100 µg
24329SB Anti-NORE1 h. r. m. WB, IHC Ras effector, member of RASSF1 gene family 100 µg
3319PR Anti-OMI (Htr2A) h. WB IAP inhibitor 100 µg
3152PR Anti-PHAP (CT) h.m.r. WB Regulator of mitochondrion apoptosis 100 µg
3149PR Anti-PHAP (NT) h. m. r. WB Regulator of mitochondrion apoptosis 100 µg
3151PR Anti-PHAP I (CT) h. m. r. WB Regulator of mitochondrion apoptosis 100 µg
3147PR Anti-PHAP III h. m. r. WB Regulator of mitochondrion apoptosis 100 µg
3321PR Anti-PIKE (CT) (centaurin gamma 1) h. m. WB Apoptosis inhibitor 100 µg
24277SB Anti-PUMA h. m. WB,IHC A novel member in Bcl2-family 100 µg
3041PR Anti-PUMA (CT) h. m. WB A novel member in Bcl-2 family 100 µg
3043PR Anti-PUMA (NT) h. WB A novel member in Bcl-2 family 100 µg
1117PR Anti-RAIDD (CT) h. WB Cell death adapter molecule 100 µg
1115PR Anti-RAIDD (IN) h. WB Cell death adapter molecule 100 µg
2183PR Anti-RICK (CT) h. WB RIP-like interacting CLARP kinase 100 µg
2075PR Anti-RICK (NT) h. WB RIP-like interacting CLARP kinase 100 µg
2283PR Anti-RIP3 m. r. WB Mouse receptor interacting protein 100 µg
2409PR Anti-Smac (CT) h. m. r. WB (DIABLO) IAPs binding protein 100 µg
2143PR Anti-SODD (NT) h. WB Silencer of death domain 100 µg
24283SB Anti-Survivin h. WB,IHC New inhibitor of apoptosis 100 µg
2235PR Anti-Survivin (CT) h. WB New inhibitor of apoptosis 100 µg
2233PR Anti-Survivin (NT) h. WB New inhibitor of apoptosis 100 µg
1131PR Anti-TACE (CT) h. m. r. WB TNF-alpha converting enzyme 100 µg
2395PR Anti-TACI h. WB Receptor for BAFF and APRIL 100 µg
3109PR Anti-TL1A (NT) h. m. r. WB DR3 ligand 100 µg
1113PR Anti-TRAIL (CT)** h. WB Ligand for DR4 and DR5 100 µg
24172SB Anti-TRAIL (CT)** h. WB,IHC Ligand for DR4 and DR5 100 µg
24171SB Anti-TRAIL (NT) h. WB,IHC Ligand for DR4 and DR5 100 µg
24296SB Anti-TRAIL-R2 h. IHC Novel TNF family member that induces apoptosis 100 µl
24297SB Anti-TRAIL-R3 h. IHC Novel TNF family member that induces apoptosis 100 µl
24298SB Anti-TRAIL-R4 h. WB,IHC Novel TNF family member that induces apoptosis 100 µg
3207PR Anti-XAF-1 (CT) h. m. WB Inhibitor of XIAP 100 µg
3409PR Anti-XAF-1 (IN) h. WB Inhibitor of XIAP 100 µg
3331PR Anti-XIAP (CT) h. m. WB Apoptosis inducing kinase 100 µg
2067PR Anti-ZIPK (IN) h. WB Apoptosis inducing kinase 100 µg
53 network
2391PR Anti-Chk2 (NT) h. m. r. WB A novel check point kinase 100 µg
2447PR Anti-MTBP (IN2) h. WB MDM2 binding protein 100 µg
2451PR Anti-PERP (NT)** h. WB Mediator of p53 induced apoptosis 100 µg
24284SB Anti-PERP** h. WB,IHC Mediator of p53 induced apoptosis 100 µg
2443PR Anti-PID/MTA2 h. m. r. WB Involved in p53 deacetylation 100 µg
3045PR Anti-p53DINP1, SIP h.m.r. WB Apoptosis-associated p53 target 100 µg
2383PR Anti-p53R2 (NT) h. m. r. WB A novel ribonucleotide kinase 100 µg
Toll-like receptors
3395PR Anti-BTK (NT) (ATK, BPK) h. m. WB Bruton's Tyrosine Kinase 100 µg
3377PR Anti-ECSIT (CT) h. m. WB An intermediate in the TLR and Bmp signaling pathways 100 µg
3289PR Anti-MD-2 (IN) h. m. r. WB, IHC Toll-like receptor adaptor protein 100 µg
3295PR Anti-SARM (CT) h. m. WB, IHC Toll-like receptor adaptor protein 100 µg
3367PR Anti-SIGIRR (CT) h. m. WB A TLR inhibitor
3363PR Anti-ST2 (NT) m. WB A TLR inhibitor 100 µg
3387PR Anti-TAB1 h. m. WB TAK1 binding protein
3157PR Anti-TIRAP (CT) h. m. r. WB, IHC Toll-like receptor adaptor protein 100 µg
3155PR Anti-TIRAP (IN) (MAL) h. WB Toll-like receptor adaptor protein 100 µg
3206PR Anti-TIRP (CT) h. WB Toll-like receptor adaptor protein 100 µg
3299PR Anti-TIRP (C2) h. m. r. WB Toll-like receptor adaptor protein 100 µg
3135PR Anti-TLR2 (NT) h. m. WB, IHC Toll-like receptor 100 µg
3141PR Anti-TLR4 (NT) h. WB Toll-like receptor 100 µg
3269PR Anti-TLR7 (IN) h. m. WB Toll-like receptor protein 100 µg
3281PR Anti-TLR8 (IN) h. m. WB Toll-like receptor protein 100 µg
3275PR Anti-TLR10 (IN) h. WB Toll-like receptor protein 100 µg
3277PR Anti-TLR11 (CT) m. WB Toll-like receptor protein 100 µg
3285PR Anti-TLR11 (IN) m. WB Toll-like receptor protein 100 µg
3371PR Anti-TRIAD3A h. WB A TLR-ubiquitinating enzyme 100 µg
3173PR Anti-TRIF (TICAM-1) h. WB Toll-like receptor adaptor protein 100 µg
3373PR Anti-UBC13 (E2N) h. m. r. WB Ubiquitin conjugating enzyme 13 100 µg
3375PR Anti-UEV1A h. m. r. WB An ubiquitin conjugating enzyme 100 µg
shipped on blue ice; stored at -20°C
(once thawed, stored at 4°C to avoid multiple freezing and thawing)
Abbreviations: * h.: human, m.: mouse, r. : rat,
tested in: WB: Western blot, IP: immunoprecipitation,IHC: immunohistochemistry,
AI: apoptose induction, I: inhibition,
CT: C-terminus, NT: N-terminus, IN: intermediate domain, ED: extracellular domain,
ID: intracellular domain.
Control lysates of cell lines and tissues and blocking peptides are available for testing upon request.
**: different target antigens.

Control Antibodies

All control immunoglobulins are obtained from serum of animals that have not been immunized. The antibodies were purified by DEAE-column chromatography.


For a detailed data sheet as a pdf-file, please click on the product No.

LIST OF ANTIBODIES: ORDER INFORMATION, SHIPPING AND STORAGE
3703PR Normal Rabbit IgG Antibody 100 µg
3705PR Normal Goat IgG Antibody 100 µg
3707PR Normal Chicken IgY Antibody 100 µg
100 µg is supplied in 100 µl of PBS containing 0.02% sodium azide. Store at 4°C, stable for one year.


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