products | cell biology and antibodies | Antibodies for Neurobiology

Cell Biology and Antibodies

Antibodies for Neurobiology

Features:

• very cost-effective
• thoroughly tested in different immunological applications
   
  

Background:

Common neurological and neurodegenerative diseases, e.g. epilepsy, Alzheimer`s disease or ischemia often result from distinct neurophysiological disorders which might potentiate and lead to irreversible defects in the central nervous system (CNS) such as neuronal cell death.

Thus, a better understanding of the neuronal interactions, pathways and their control will provide means for the therapy of certain disorders affecting one or more components of this crucial system. We therefore offer an exceptional range of antibodies for the detection of certain proteins and compounds which play important roles in the CNS, e.g. as receptors, transmitters or neurotoxins. 

Antibodies against receptors and peptides in CNS research

Polyclonal Antibodies Against:

• neurotrophic factor receptors
• peptides important in alzheimer´s desease
   
  

For a detailed data sheet as a pdf-file, please click on the product No.

LIST OF ANTIBODIES: ORDER INFORMATION, SHIPPING AND STORAGE
order #	product	reactive*	applic.*	description	amount
24357SB	Anti-Alivin 1	h. m. r.	WB, IHC	Ali 1 promotes survival of neurons	100 µg
2133PR	Anti-APP (Abeta-NT)	h. m. r.	WB	Amyloid protein precursor	100 µg
2136PR	Anti-APP (CT)	h. m. r.	WB	Amyloid protein precursor	100 µg
24142SB	Anti-Artemin (IN)	h.	WB, IHC	Novel member of the GDNF family	100 µg
24125SB	Anti-Artemin (NT)	h.	WB, IHC	Novel member of the GDNF family	100 µg
2253PR	Anti BACE (CT)	h.	WB	Beta-site APP cleaving enzyme	100 µg
2249PR	Anti-BACE2 (CT)	h. m. r.	WB	Beta-site APP cleaving enzyme 2	100 µg
2247PR	Anti-BACE2 (NT)	h. m. r.	WB	Beta-site APP cleaving enzyme 2	100 µg
24306SB	Anti-CLAC-P (NC2-1 region)	h. m.	WB, IHC	collagen-like Alzheimer amyloid plaque component	100 µg
24307SB	Anti-CLAC-P (NC2-2 region)	h. m.	WB, IHC	collagen-like Alzheimer amyloid plaque component	100 µg
24145SB	Anti-GABA-RAP (NT)**	h.	WB, IHC	Reacts with GABA receptor-associated protein	100 µg
24146SB	Anti-GABA-RAP (NT)**	h.	WB, IHC	Reacts with GABA receptor-associated protein	100 µg
24147SB	Anti-GABA-RAP (NT)**	h.	WB, IHC	Reacts with GABA receptor-associated protein	100 µg
1133PR	Anti-GFRalpha-1 (IN)	h. m. r.	WB	GDNF receptor	100 µg
1135PR	Anti-GFRalpha-2 (IN)	h. m. r.	WB	Neurturin receptor	100 µg
1137PR	Anti-GFRalpha-3 (IN)	m.	WB	Persephin receptor	100 µg
24205SB	Anti-HAP40	h.	WB, IHC	40 kDa Huntingtin-associated protein	100 µg
24121SB	Anti-Neuronal NO Synthase	h.	WB, IHC	Reacts with human variant of nNOS	100 µg
1121PR	Anti-Neurturin (CT)	h.	WB	Ligand for GFRalpha-2	100 µg
24133SB	Anti-NFH	h.	WB, IHC	Involved in amyotrophic lateral sclerosis	100 µg
24224SB	Anti-NPFF1 Receptor	h.	WB, IHC	Neuropeptide FF is involved in pain modulation	100 µg
24225SB	Anti-NPFF2 Receptor	h.	WB, IHC	G protein coupled receptor	100 µg
24120SB	Anti-PHF-2	h.	WB, IHC	Reacts with leukemia associated protein	100 µg
24179SB	Anti-Shank1a (NT)	h.	WB, IHC	NMDA binding protein	100 µg
24359SB	Anti-Rattin (Humanin-like)	r.	WB, IHC	Peptide against neuronal cell death	100 µg
shipped on blue ice; store at -20°C (once thawed, store at 4°C to avoid multiple freezing and thawing) Abbreviations: * h.: human, m.: mouse, r. : rat, tested in: WB: Western blot, IP: Immunoprecipitation, IHC: Immunohistochemistry, AI: apoptose induction, I: Inhibition, CT: C-terminus, NT: N-terminus, IN: internal, ED: extracellular domain, ID: intracellular domain. Control lysates of cell lines and tissues and blocking peptides are available for testing upon request.

Antibodies against neurotoxins and neurotransmitters

Polyclonal Antibodies Directed Against:

• catecholaminergic molecules
• indolaminergic molecules
• amino acids and derivatives
• polyamine molecules
• neurotoxins, drugs and anti-oxydants
• nitro and nitroso compounds
  

Antisera were raised in rabbits after immunization with the respective conjugated molecules (antigen linked to a protein carrier). Each antibody raised was purified and characterized by competition experiments with different conjugated close to homologue molecules. The antibodies are highly specific, show strong affinities and were usually tested in ELISA, immunohistochemistry and Western blots.
 
 

For a detailed data sheet as a pdf-file, please click on product No.

LIST OF ANTIBODIES: ORDER INFORMATION, SHIPPING AND STORAGE
POLYCLONAL ANTIBODIES
order #	description	reactive*	amount
Catecholaminergic molecules
1070GE	Anti-conjugated 6-hydroxy-dopamine	rabbit	50 µl
1061GE	Anti-conjugated adrenalin	rabbit	50 µl
1000GE	Anti-conjugated dopamine	rabbit	50 µl
1001GE	Anti-conjugated L-dihydroxyphenylalanine	rabbit	50 µl
1002GE	Anti-conjugated noradrenaline	rabbit	50 µl
1003GE	Anti-conjugated octopamine	rabbit	50 µl
1005GE	Anti-conjugated p-tyramine	rabbit	50 µl
1004GE	Anti-conjugated tyrosine	rabbit	50 µl
Indolaminergic molecules
1056GE	Anti-conjugated 4,5-dihydroxytryptamine	rabbit	50 µl
1082GE	Anti-conjugated 5,6-dihydrotryptamine	rabbit	50 µl
1006GE	Anti-conjugated 5-hydroxytryptamine	rabbit	50 µl
1007GE	Anti-conjugated 5-hydroxytryptophan	rabbit	50 µl
1050GE	Anti-conjugated 5-hydroxytryptophol	rabbit	50 µl
1008GE	Anti-conjugated 5-methoxytryptamine	rabbit	50 µl
1033GE	Anti-conjugated 5-methoxytryptophan	rabbit	50 µl
1032GE	Anti-conjugated 6-hydroxtryptamine	rabbit	50 µl
1009GE	Anti-conjugated tryptamine	rabbit	50 µl
1010GE	Anti-conjugated tryptophan	rabbit	50 µl
Amino acids and derivatives
1088GE	Anti-conjugated D-alanine	rabbit	50 µl
1034GE	Anti-conjugated arginine	rabbit	50 µl
1011GE	Anti-conjugated aspartate	rabbit	50 µl
1035GE	Anti-conjugated beta-alanine	rabbit	50 µl
1012GE	Anti-conjugated cysteine	rabbit	50 µl
1055GE	Anti-conjugated D-aspartic acid**	rabbit	50 µl
1090GE	Anti-conjugated D-aspartic acid (D-aspartate)**	rabbit	50 µl
1079GE	Anti-conjugated D-biotin	rabbit	50 µl
1089GE	Anti-conjugated D-glutamate	rabbit	50 µl
1081GE	Anti-conjugated D-pantothenic acid	rabbit	50 µl
1064GE	Anti-conjugated D-serine**	rabbit	50 µl
1087GE	Anti-conjugated D-serine**	rabbit	50 µl
1013GE	Anti-conjugated GABA	rabbit	50 µl
1014GE	Anti-conjugated glutamate	rabbit	50 µl
1015GE	Anti-conjugated glycine	rabbit	50 µl
1016GE	Anti-conjugated histamine	rabbit	50 µl
1036GE	Anti-conjugated histidine	rabbit	50 µl
1037GE	Anti-conjugated homocysteic acid	rabbit	50 µl
1017GE	Anti-conjugated homocysteine	rabbit	50 µl
1067GE	Anti-conjugated L-glutamine	rat	50 µl
1071GE	Anti-conjugated L-isoleucine	rabbit	50 µl
1065GE	Anti-conjugated L-leucine	rabbit	50 µl
1072GE	Anti-conjugated L-threonine	rabbit	50 µl
1069GE	Anti-conjugated L-valine	rabbit	50 µl
1018GE	Anti-conjugated methionine	rabbit	50 µl
1062GE	Anti-conjugated N-acetyl-cysteine	rat	50 µl
1019GE	Anti-conjugated phenylalanine	rabbit	50 µl
1020GE	Anti-conjugated serine	rabbit	50 µl
1021GE	Anti-conjugated taurine	rabbit	50 µl
1078GE	Anti-conjugated Trans-hydroxyproline	rabbit	50 µl
order #	description	reactive*	amount
Other conjugated small-sized molecules
1023GE	Anti-conjugated acetylcholine	rabbit	50 µl
1049GE	Anti-conjugated acrolein	rabbit	50 µl
1048GE	Anti-conjugated azelaic acid	rabbit	50 µl
1086GE	Anti-conjugated capric acid	rat	50 µl
1084GE	Anti-conjugated caproic acid	rat	50 µl
1085GE	Anti-conjugated caprylic acid	rat	50 µl
1063GE	Anti-conjugated diamino-pentane	rabbit	50 µl
1058GE	Anti-conjugated formaldehyde	rat	50 µl
1022GE	Anti-conjugated glutathione	rabbit	50 µl
1057GE	Anti-conjugated kynurenic acid	rabbit	50 µl
1038GE	Anti-conjugated malondialdehyde	rabbit	50 µl
1051GE	Anti-conjugated phenyl acetic acid	rabbit	50 µl
1066GE	Anti-conjugated quinolinic acid	rabbit	50 µl
Conjugated polyamine molecule
1059GE	Anti-conjugated carnosine	rabbit	50 µl
1024GE	Anti-conjugated ornithine	rabbit	50 µl
1047GE	Anti-conjugated spermine	rabbit	50 µl
Conjugated anti-oxydants
1039GE	Anti-conjugated retinoic acid	rabbit	50 µl
Neurotoxins, drugs and other chemicals
1040GE	Anti-conjugated acetyl salicylic acid	rat	50 µl
1041GE	Anti-conjugated nitrendipine	rabbit	50 µl
1073GE	Anti-conjugated tetrodotoxin	rabbit	50 µl
Nitro and nitroso compounds
1042GE	Anti-conjugated citrulline	rabbit	50 µl
1027GE	Anti-conjugated NO2-serotonine	rabbit	50 µl
1026GE	Anti-conjugated NO2-tyrosine	rabbit	50 µl
1046GE	Anti-conjugated NO-acetyl salycylic acid	rat	50 µl
1053GE	Anti-conjugated NO-dopamine	rat	50 µl
1044GE	Anti-conjugated NO-glutathion	rat	50 µl
1028GE	Anti-conjugated NO-histidine	rabbit	50 µl
1060GE	Anti-conjugated NO-L-DOPA	rat	50 µl
1068GE	Anti-conjugated NO-L-glutamine	rat	50 µl
1025GE	Anti-conjugated NO-lysine	rabbit	50 µl
1052GE	Anti-conjugated NO-methionine	rat	50 µl
1043GE	Anti-conjugated NO-tryptophan	rabbit or rat	50 µl
1054GE	Anti-conjugated NO-tyramine	rat	50 µl
1045GE	Anti-conjugated NO-tyrosine	rabbit	50 µl
Vitamines
1093GE	Anti-conjugated folic acid (B vitamin)	rat	50 µl
1092GE	Anti-conjugated riboflavin (vitamin B2)	rat	50 µl
1091GE	Anti-conjugated thiamine (vitamine B1)	rat	50 µl
MONOCLONAL ANTIBODIES
1030GE	Anti-conjugated acetylcholine	mouse	50 µl
1094GE	Anti-conjugated DL-5-hydroxytryptophan	mouse	50 µl
1029GE	Anti-conjugated dopamine	mouse	50 µl
1031GE	Anti-conjugated glutamate	mouse	50 µl
1083GE	Anti-conjugated histamine	mouse	50 µl
1080GE	Anti-conjugated L-DOPA (monoclonal)	mouse	50 µl
** different antigen targets shipped on blue ice; store at -20°C (once thawed, store at 4°C to avoid multiple freezing and thawing)

 
See also chapter 5 of our online catalog.