Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology

MoBiTec - Product Highlights - NEWS

2018

Dec-05: Get a New Perspective on Gi Signaling

Monitor inhibition of cAMP production in real time, in any cell type. Ultimately, it is the balance between stimulation and inhibition that controls the cell, but until now we have never been able to watch in real time, the competition between Gs and Gi. Now we can!

more...


Nov-09: Lupus Drug Discovery

Transcreener ADP2 assay enables evaluation of NIK inhibitors for lupus drug discovery; Systemic lupus erythematosus (SLE), or lupus, takes a devastating toll. An autoimmune disease that triggers a dysfunctional immune system to attack its own tissues. SLE strikes young women most often. Both genetic and environmental risk factors are suspected...

Read more...


Nov-07: New Partner: Elabscience

Proteins, Antibodies, ELlSA Kits, CLIA Kits, Labeling Kits, Biochemical Kits & more; large selection of products with a wide range of species reactivity; products are cited in top journals.

more...



Nov-05: New Partner: Hispanagar

Bacteriological, pharmaceutical, and alimentary agar; superior agars and a top range of premium agaroses for use in immunodiffusion, electrophoresis, chromatography, and other applications.

more...


Oct-19: New Partner: Ion Indicators

Pure, high quality indicators to empower better research results in life science, neuroscience, and drug discovery: calcium, potassium, sodium, and pH indicators are available.

more...


Oct-12: Fluorescence Labeling & Detection

ABP Biosciences - a spin-off company from Molecular Probes - offers high-quality products at reasonable prices. New comprehensive product brochures are now available.

more...


Sept-28: New Mitochondrial Peptides –
For Aging and Disease Research

Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated...

Discover more !


Sept-26: Powering Drug Discovery at Pfizer

The impact of Acetyl-CoA carboxylases (ACCs) on eukaryotic metabolism and metabolic-related disease states is profound. Inhibition of ACC isoforms could be advantageous for lessening many cardiovascular risk factors linked to obesity, diabetes, insulin resistance, and metabolic syndrome. This strategy has captured the attention of pharmaceutical giant Pfizer, which has filed a series of patent applications relating to ACC inhibitor compounds. Each patent and patent application details the use of Transcreener® ADP2 FP Assay in a screen to measure inhibition...

Read more !


Sept-04: Membrane Protein Research

Styrene - maleic acid (SMA) copolymers are broadly used for function and structure studies of membrane proteins. The significant advantages of using SMA copolymers include generating a detergent-free system and forming bilayer nanodiscs with phospholipids.

more...


Sept-03: Newsletter XXVII

Newsletter XXVII

PDF


Aug-15: Neurodegenerative Diseases

AnaSpec’s core expertise in neuroscience enables the development of peptides, assay kits, recombinant proteins, and antibodies, all offered as integrated proteomic tools to advance neurodegenerative disease research.

Alzheimer’s Disease Portfolio (PDF)


Aug-14: Coagulation Assay Kits

Plasma Kallikrein Activity Assay Kit - sensitive detection of human plasma kallikrein and inhibitor screening.

more...

White Paper:
How is Cardiovascular Health Influenced by Peptides of the Blood Coagulation Pathway? (PDF)


July-02: Infectious Serology

ELISA kits for the detection of specific IgG antibodies against polyomavirus JC (JCV) and polyomavirus BK (BKV) in human serum and plasma (CE/IVD-certified).

more...


June-29: Protein-Lipid Interaction

New class of lipid microparticles; small enough to be used in phagocytosis experiments! Phosphatidylserine (PS), Phosphatidylcholine (PC), and PC/PS microparticles have phospholipids attached in a unique way allowing headgroups to be exposed and available for the study of biological interactions.

more...


June-08: New Antimicrobials Against Gram-Negative Pathogens

Gram-negative bacterial pathogens pose grave dangers in clinical and environmental settings alike. An estimate of the prevalence of infections due to MDR gram-negative bacilli indicated profound consequences for patient mortality, hospital length of stay, and increased hospital costs. By 2050, it has been estimated that multidrug resistance (in total) will be responsible for 300 million deaths. MsbA - an ABC transporter protein - is critical for virulence, and loss of MsbA function causes rapid membrane disruption and cell death. A library of approximately 3 million small molecules for specific inhibitors of Escherichia coli MsbA was screened. The researchers also used the Transcreener ADP2 FP ATPase Assay from our partner BellBrook Labs.

more...


June-01: New Partner

ABP Biosciences - a spin-off company from Molecular Probes - is specialized in fluorescence labeling and detection technologies. They offer high-quality products at reasonable prices.
Learn more about their Cell Imaging Probes!


May-30: New LPA Antibody

Lysophosphatidic Acid (LPA) is a serum-derived phospholipid involved in diverse cellular processes. Recent research indicates LPA may play a significant role in the pathophysiology of cancer and may be used as a biomarker for ovarian cancer. The LPA antibody is validated for use in IHC, ICC, and ELISA.

Technical Datasheet


Apr-13: Transfection Optimization Protocol & Special Papers

 • DNA Transfection Optimization Protocol  PDF
 • Transfection Applications for Stem Cells  PDF
 • Gene Expression and Cytotoxicity Analysis of    Transfection Reagents  PDF
 • Selecting a Transfection Reagent for Large    Scale Protein Production  PDF


Mar-28: Mitophagy Detection in Living Cells

Mitophagy is the process of selective mitochondrial degradation by autophagy that has been found to be involved in many cancers and neurodegenerative diseases. MBL International’s Keima-Red fluorescent vector provides a simple method for detecting mitophagy in living cells by using a unique excitation profile. Learn more about this vector in their new video.

more...


Mar-28: Newsletter XXVI

Newsletter XXVI

PDF


Mar-26: Assess Cell Viability, Cell Proliferation, and Cytotoxicity

AquaBluer – Fluorescent redox indicator for cell viability and cytotoxicity assays; costs 3x less than Alamar Blue and 26x less than MTT assay.
Free samples available!

more...


Jan-19: Fluorescent Detection of Cellular Stress & Toxicity

The Live Cell Stress Sensor detects cellular stress and unfolded protein response; for monitoring stress in diseases or detecting drug-based cellular toxicity.

more...


Jan-10: Accelerate Epigenetic Drug Discovery

Methyltransferases have become a major focus of drug discovery for cancer and other diseases driven by epigenetic factors. BellBrook Labs’ new, ultra-sensitive AptaFluor™ SAH Methyltransferase Assay eliminates cost and sensitivity barriers that are slowing the discovery of methyltransferase inhibitors.

more...

2017

Dec-13: Autophagy

Launch of p62 ELISA Kits:
Our partner MBL is the only supplier of p62 ELISA Kits that target p62 phosphorylated at Ser349 and Ser403. These kits support your research on autophagy, autoimmune diseases, Alzheimer’s, Parkinson’s, and hepatocellular carcinoma (a type of liver cancer).

more...


Nov-17: Virus Production

Produce high functional adeno-associated virus titers with TransIT®-VirusGEN™ Transfection Reagent!

More information or request a FREE sample


Oct-13: CyLyte Fluor Dyes

A cost effective replacement for Cy® dyes! Suitable for labelling proteins, antibodies, peptides, oligonucleotides, DNA, and small molecules.

more...


Oct-13: Next Generation Calcium Indicators

Red-fluorescent and near-infrared fluorescent probes for highly sensitive detection of calcium ions. Suitable for multi-color and in vivo imaging.

more...


Sept-11: Newsletter XXV

Newsletter XXV

PDF


Aug-28: Specific Detection of ß-Galactosidase

GlycoYELLOW™-ßGal is a fluorescent probe for detection of ß-galactosidase. For selection of cells and tissues transfected with lacZ and for live-cell imaging of Senescence-associated beta-galactosidase.

more...


Aug-25: QuickSwitch™ Custom Tetramer Kits

Rapid, high-quality creation of custom class I tetramers is now a reality! Create new specificity tetramers in just a few hours.

more...


Aug-11: Fluorescent Probes for Inorganic Biochemistry

Fluorescent probes for specific detection of Fe2+, Cu+, and Zn2+ ions in living cells.

more...


Aug-11: VectorBuilder

A free and versatile online tool for outsourcing your cloning projects; follow the highly intuitive workflow on VectorBuilder to design your desired vector with just a few mouse clicks.

more...


July-26: Exosome Research

Since 2007 HansaBioMed offers optimized solutions for exosome research. Their products are now available at MoBiTec:
 • Lyophilized Exosome Standards   more...
 • Exosome Quantification Kits   more...
 • Exosome Isolation Tools   more...
 • HansaBioMed - Complete Catalog   (PDF)


July-25: Measuring Multiple Signaling Pathways Inside a Living Cell – in Real Time!

G protein-coupled receptors trigger signaling pathways that affect all kinds of biological functions in nearly every cell type. A method to understand these basic cellular mechanisms in health and disease involves fluorescent biosensors that measure intracellular GPCR signaling.

more...


June-14: Proteomics – New Brochures Available

 • Protein iDentification (PDF)
 • Peptides (PDF)
 • TR-FRET (PDF)


June-14: Recombinant Proteins Related to Neuroscience Research

EndoClear™ and EndoClear™ Plus
The lowest endotoxin levels in research-grade alpha-synuclein.

more...


Apr-28: Food Grade Protein Production

Bacillus subtilis Food Grade Expression System: stable high- or low-level expression without addition of any antibiotics.

more...


Apr-06: Newsletter XXIV

Newsletter XXIV

PDF


Mar-24: Protein Labeling Kits for TR-FRET

Conveniently conjugate your proteins for TR-FRET assays: fast labeling stable dye-protein conjugates ideal for HTS all essential components for conjugation and purification included

more...


Mar-10: Exclusive Inhibitor Screen for Phospholipidosis (PL)

Inhibition of Lysosomal Phospholipase A2 (LPLA2) by a drug candidate can predict its potential to cause drug-induced PL, a serious side effect resulting in tissue inflammation and organ damage. The LPLA2 Inhibitor Screen is a fluorogenic assay designed to identify problematic compounds early in the drug discovery process.

more...


Feb-03: Reactive Oxygen Species

Fluorescent probes for highly selective detection of single reactive oxygen species (ROS).

more...


Jan-10: Exosome Research

ExoCap™ kits are designed for exosome isolation and enrichment and are optimized for use with serum, plasma and cell culture supernatants.

more...

2016

Dec-07: Stem Cell Transfection Solutions

Transfection of nucleic acids such as plasmid DNA, mRNA, and siRNA serves as a vital tool in stem cell reprogramming and differentiation processes. Mirus Bio reagents enable high efficiency transfection of stem cells. Prove it to yourself! Request a FREE Sample!

more...


Nov-11: Alcohol Abuse –
New Therapeutic Target for Liver Fibrosis

BellBrook Labs awarded NIH grant to validate new target for liver fibrosis using Transcreener GTPase assay platform
Press Release
Learn more about the assay:
Transcreener GDP Assay


Oct-12: GelBox

All-in-one portable electrophoresis and imaging system data access by WLAN on mobile device uses disposable gel cassettes

more...


Oct-11: MagSi-DNA Vegetal

Magnetic bead-based isolation of genomic DNA from plant tissues; applicable both for manual or automated use

more...


Oct-07: Sequencing Clean-Up

Optima DTR™ - Dye Terminator Removal System: Cost-effective solution for high throughput applications; available as gel filtration plates and 8-well strips

more...


Sept-28: RNA Silencing

Easy silencing or regulation of mRNA, miRNA, or long non-coding RNA targets; no need to use transfection reagents; especially for difficult to transfect cells and animal models

more...


Sept-09: Glycan Analysis

New Glycan Array Kit for determining the glycan binding profile of proteins, eukaryotic cells, viruses, spores, bacteria & parasites

more...


Aug-17: Virus Production

TransIT®-Lenti Transfection Reagent – Ideal for Recombinant Lentivirus Production

more...


Aug-12: Newsletter XXIII

Newsletter XXIII

PDF


July-28: Live-Cell Super-Resolution Imaging

New fluorescent probe - HMSiR - overcoming the problems of dSTORM: performing super-resolution imaging with low-power excitation light and without additives

more...


July-08: ELISA Kits for Cell Biology Research

More than 6,500 high quality ELISA kits at an affordable price !

more...


June-29: CRISPR Application Support

New brochure to highlight CRISPR. This customer facing piece provides an overview of CRISPR methodology, a glossary of terms, and transfection solutions.

PDF


June-17: Inhibitors and Compound Libraries

Inhibitors and compound libraries for studying cell signaling pathways and for drug screening.


June-01: Speed Up Your Western!

SpeedBlot (Mouse) Western Blot Stain: Ready-to-use reagent for the detection of primary mouse antibodies in blot assays

more...


Apr-22: New CRISPR White Paper

This new paper on various methods to apply CRISPR outlines the following:
Overview of CRISPR/Cas9 technology Brief comparison of genome editing technologies including ZFNs, TALENs, and CRISPR Delivery solutions and data for DNA, RNA, or RNP CRISPR delivery formats

PDF


Apr-20: Magnetic Silica Beads

Couple the biological molecule of your choice! M-Beads Direct: paramagnetic beads and surface coating reagents for custom functionalization

more...


Apr-15: Newsletter XXII

Newsletter XXII

PDF


Apr-6: Fluorescent Biosensors

Genetically encoded sensors for cell-based assays and live cell imaging. These probes are used for drug discovery and to observe and measure cell signaling processes.

more...


Mar-29: One-Step qPCR Kits

Running all steps in one tube: nucleic acid extraction, purification, and detection – simply the quickest qPCR detection kits!

more...


Mar-21: Hypoxia Detection Probe for Cancer and Ischemia Research

Fluorogenic imaging probe for detection of hypoxia. Suitable for live-cell imaging, flow cytometry, and tissue experiments.

more...


Mar-09: Proteasome Inhibitors

The proteasome is a promising target for treatment of cancer and autoimmune diseases. MoBiTec offers a large selection of proteasome & immunoproteasome specific inhibitors.

more...


Feb-26: Genome Editing Using CRISPR/Cas

To learn more about the basic mechanism of CRISPR/Cas9 genome editing and the key points affecting decisions about whether to deliver Cas9 and guide RNA in plasmid, RNA, or RNP format, please visit our new CRISPR/Cas9 Genome Editing application site.


Feb-03: Zika Virus Real-Time RT-PCR Kit

A precise, fast, and reliable diagnostic test for the detection of Zika virus in serum or plasma; compatible with several cycler systems available on the market.

more...


Jan-29: Newsletter XXI

Newsletter XXI

PDF