Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology

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M-Beads Magnetic Silica Beads

M-Beads Magnetic Silica Beads for Proteomics

Overview on different M-Beads Magnetic silica beads

Overview on different M-Beads Magnetic silica beads. To enlarge please point with mouse.

Features

  • Highly monodisperse
  • No aggregation
  • Adjustable magnetic moments
  • Adjustable surface properties
  • Efficiently automatable
  • Neutral optical properties

Description

  • M-Beads Magnetic silica beads are specifically designed for separation, concentration and purification of biomolecules, specific cells or cell compartments. They are ideally suited as a solid phase in assay kits. Due to a fast and flexible production process unrestricted customization possibilities with regard to sizes, kinetics, optical, surface and binding properties are facilitated.

  • M-Beads Magnetic silica beads C4, C8 and C18 are an ideal tool for the purification, concentration and desalting of peptides and protein digests. The surface of the beads has been modified with C4, C8 and C18 alkyl groups that are typical for reversed phase applications.
  • M-Beads Magnetic silica beads WCX (weak cation exchange) magnetic beads have the typical ion exchange properties well known from classical chromatography. Protein and peptides are charged at the surface and will be adsorbed to magnetic beads under low salt condition. Under high salt conditions or by pH shift the target proteins/peptides are eluted (ion exchanged). Due to the different binding/elution mechanisms the M-Beads Magnetic silica beads WCX are a powerful alternative to the M-Beads magnetic silica beads C4, C8 and C18
  • M-Beads Magnetic silica beads WAX (weak anion exchange) magnetic beads are the "counter" beads to the M-Beads WCX beads. Binding, washing and elution are also triggered by the protein/peptide total net charge. The M-Beads WAX beads are ideally suited when more acidic proteins/peptides are expected in the sample. However, our protocols given in the corresponding product sheet cover buffer systems for acidic, neutral and basic conditions.
  • M-Beads Magnetic silica beads WCX are magnetic silica beads with a high magnetic content optimized for protein and peptide separation. Since the M-Beads WCX and M-Beads WAX act as counter-beads, MoBiTec recommends testing both types of beads, to see which suits best in your individual application.

Dynabead® replacement guide for M-Beads Magnetic Silica Beads

  • MoBiTec delivers with its M-Beads products a perfect solution for replacing the corresponding Dynabeads®, of which some are discontinued by Invitrogen, without major changes in protocols or handling.
Invitrogen / Dynal MoBiTec
Order# Product Amount (ml) Order # Product Amount (ml) Remarks
105-11D Dynabeads® WCX 2  PR-MAG00042-01 M-Beads Magnetic silica beads WCX 2 *
105-15D Dynabeads® SCX 2  PR-MAG00042-01 M-Beads Magnetic silica beads WCX 2 *
105-15D Dynabeads® SAX 2  PR-MAG00043-01 M-Beads Magnetic silica beads WAX 2 *
102-11D Dynabeads® RPC 18 2  PR-MAG00004-01

PR-MAG00041-01
M-Beads Magnetic silica beads proteomics C18

 M-Beads Magnetic silica beads proteomics C8
2

2
* / **
102-16D Dynabeads® RPC protein 2  PR-MAG00040-01

 PR-MAG00041-01
M-Beads Magnetic silica beads proteomics C4
M-Beads Magnetic silica beads proteomics C8
2

2
* / **
370-02D Dynabeads® MyOne silane 5  PR-MAG00001-01 M-Beads Magnetic silica beads S 1.0 2 ***
650-11 Dynabeads® MyOne carboxylic acid 2  PR-MAG00011-01 M-Beads Magnetic silica beads S-COOH 1.0 2 ***
143-05D Dynabeads® M-270 carboxylic acid 2  PR-MAG00011-01 M-Beads Magnetic silica beads S-COOH 1.0 2 ***
143-07D Dynabeads® M-270 Amine 2  PR-MAG00013-01 M-Beads Magnetic silica beads S-NH2 1.0 2 ***
100-01D Dynabeads® Protein A for immunopr. 1  PR-MAG00024-01 M-Beads Magnetic silica beads protein A 1.0 2 ***
100-03D Dynabeads® Protein G for immunopr. 1  PR-MAG00028-01 M-Beads Magnetic silica beads protein G 1.0 2 ***
656-01 Dynabeads® MyOne™ Streptavidin C1 2  PR-MAG00031-01 M-Beads Magnetic silica beads STA 1.0 2 ***
650-01 Dynabeads® MyOne™ Streptavidin T1 2  PR-MAG00031-01 M-Beads Magnetic silica beads STA 1.0 2 ***
653-05 Dynabeads® M-270 Streptavidin 2  PR-MAG00031-01 M-Beads Magnetic silica beads STA 1.0 2 ***
112-05D Dynabeads® M-280 Streptavidin 2  PR-MAG00031-01 M-Beads Magnetic silica beads STA 1.0 2 ***

Remarks

  • *) Discontinued by Invitrogen
  • **) To choose the right beads for your application use our M-Beads proteomics selection guide
  • ***) M-Beads are also available in 600 nm bead size to increase binding capacity and sensitivity due to larger surface. Please note that the 1.0 μm beads are combining the large surface of a 1 μm bead with high magnetic performance. M-Beads-xxx 1.0 beads can replace 2.8 μm and 1 μm beads of Invitrogen in most of the existing applications.

ORDER INFORMATION

  • For shipping and storage information please click on Order#.
Order# Description Amount Price Data Sheet
PR-MAG00040-01 M-Beads Magnetic silica beads S-C4, 1.2 um 2 ml 322,00 PDF
PR-MAG00040-02 M-Beads Magnetic silica beads S-C4, 1.2 um 10 ml 1178,00 PDF
PR-MAG00041-01 M-Beads Magnetic silica beads S-C8, 1.2 um 2 ml 322,00 PDF
PR-MAG00041-02 M-Beads Magnetic silica beads S-C8, 1.2 um 10 ml 1178,00 PDF
PR-MAG00004-01 M-Beads Magnetic silica beads S-C18 1.2 um 2 ml 322,00 PDF
PR-MAG00004-02 M-Beads Magnetic silica beads S-C18 1.2 um 10 ml 1178,00 PDF
PR-MAG00042-01 M-Beads Magnetic silica beads WCX 2 ml 357,00 PDF
PR-MAG00042-02 M-Beads Magnetic silica beads WCX 10 ml 1308,00 PDF
PR-MAG00043-01 M-Beads Magnetic silica beads WAX 2 ml 357,00 PDF
PR-MAG00043-02 M-Beads Magnetic silica beads WAX 10 ml 1308,00 PDF
  • All prices are in EURO excl. VAT and shipping. For further pricing and order information please ask your local distributor.

Download

  • Magnetic Beads Brochure (PDF)
  • M-Beads Magnetic Silica Beads WAX (PDF)
  • M-Beads Magnetic Silica Beads WCX (PDF)
  • M-Beads Magnetic Silica Beads C4, C8, C18 (PDF)