Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology


PolyPIPosomes from Echelon


Lipid bilayer structure of Control PolyPIPosomes

Lipid bilayer structure of
Control PolyPIPosomes


  • PolyPIPosomes TM are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents.


  • Uniform size (~200 nm)
  • Ready-to-use suspensions, no liposome preparation


PolyPIPosomes have demonstrated utility in a number of assay formats:

  • -Protein pull-down
  • -Surface Plasmon Resonance
  • -Liposome overlay assay
  • Control PolyPIPosomes are provided as a 1mM total lipid solution without any PIPn for use as a negative control to make sure there is no non-specific binding to the liposomes.


  • For shipping and storage information please click on Order#.
  • All prices are in EURO excl. VAT and shipping. Only available in Europe except for France and Italy.


  • Colin G. Ferguson, Robyn D. James, Cleve S. Bigman, Donnie A. Shepard, Yasmina Abdiche, Phinikoula S. Katsamba, David G. Myszka, and Glenn D. Prestwich, "Phosphoinositide-Containing Polymerized Liposomes:? Stable Membrane-Mimetic Vesicles for Protein-Lipid Binding Analysis" Bioconjugate Chem., 2005, 16 (6), pp 1475–1483.
  • Sheryl K. Elkin, Dmitri Ivanov, Mark Ewalt, Colin G. Ferguson, Sven G. Hyberts, Zhen-Yu J. Sun, Glenn D. Prestwich, Junying Yuan, Gerhard Wagner, Marjorie A. Oettinger and Or P. Gozani, "A PHD Finger Motif in the C Terminus of RAG2 Modulates Recombination Activity" The Journal of Biological Chemistry, 2005, 280, 28701-28710.