Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology

Products

Borrelia spp. Assay Kits

Borrelia spp. ELISA- and LIA-VIDITESTs

ELISA-VIDITEST anti-Borrelia

ELISA-VIDITEST anti-
Borrelia

Ixodes ricinus, carrier of Lyme disease

Ixodes ricinus, carrier of Lyme disease

Features

  • High sensitivity/specificity according to diagnostic evaluation studies
  • Highly specific recombinant antigens
  • High purity of antigens excludes of cross-reactivity with antibodies to other spirochetes
  • Quantitative and qualitative evaluation of the data
  • Intrathecal IgG, IgM synthesis determination
  • Antibody determination in serum, cerebrospinal fluid and synovial fluid

Description

  • ELISA-VIDITEST anti-Borrelia recombinant kits are intended for the detection of IgG and IgM antibodies to the pathogenic borrelia strains (B. afzelii, B. garinii and B. burgdorferi sensu stricto) in human serum, cerebrospinal fluid and synovial fluid. The detection of antibodies is one of the laboratory tests that helps to diagnose Lyme disease (LD).

  • LIA-VIDITEST anti-Borrelia kits are Line ImmunoAssay kits intended for qualitative detection of specific IgG antibodies against antigens of major pathogenic Borrelia stains (B. afzelii, B. garinii and B. burgdorferi sensu stricto) and Anaplasma phagocytophila (HGA) in human serum. The kit can be also used for indicative diagnostics of human granulocytic anaplasmosis (HGA). HGA is caused by the bacterium Anaplasma phagocytophila, which attacks white blood cells (granulocytes). Anaplasma infection can result in death for immunodefinicient, post-splenectomy or post-transplant patients. Anaplasma specific antibodies are detected in human serum by the high-specific antigen p44.

  • Anti-borrelia IgM antibodies are detectable 3 weeks after infection with its maximum during the sixth week. Subsequently, the titer of IgM antibodies decreases and IgG antibodies prevail. The detection of anti-borrelia antibodies is very important at the early stage of the disease since the typical symptoms are present only in a certain proportion of patients (e.g. erythema migraines is present in 50% of patients). The clinical symptoms of LD are similar to the symptoms of other diseases. Therefore the serology is also of use in differential diagnosis of neuroinfections, arthropathies, carditis and skin diseases. During the interpretation of the test results it has to be taken into account that the titers of antibodies at early stage of the disease are rather low and can be influenced by administration of antibiotics. Seronegativity in a small percentage of patients and the crossreactivity of antibodies elevated due to the other diseases has to be considered. Therefore, it is necessary to compare the test results with clinical data.

Overview on anti-Borrelia Antibodies

ELISA-VIDITEST RUO
Order # Product Method Evaluation No. of tests Sample Sensitivity/ Specificity
ODZ-282 anti-Borrelia recom. IgG + VlsE ELISA semiquant. 96 serum, cerebrospinal fluid 95% / 99%
ODZ-281 anti-Borrelia recomb. IgM ELISA semiquant. 96 serum, cerebrospinal fluid 99% / 97%
ODZ-172 anti-Borrelia recomb. IgG (CSF) + VlsE ELISA qualit. 96 serum, cerebrospinal fluid, synovial fluid 95% / 99%
ODZ-173 anti-Borrelia recom. IgM (CSF) ELISA qualit. 96 serum, cerebrospinal fluid, synovial fluid 99% / 97%
LIA-VIDITEST RUO
ODZ-316 anti-Borrelia IgG LIA qualit. 16 serum 100% / 98%
ODZ-317 anti-Borrelia IgM LIA qualit. 16 serum 97% / 98%

ORDER INFORMATION

  • For shipping and storage information please click on Order#.

ELISA-VIDITEST Borrelia spp.

Order# Description Amount Price Data Sheet
ODZ-282 anti-Borrelia recom. IgG + VlsE 96 wells 152,00 PDF
ODZ-281 anti-Borrelia recom. IgM 96 wells 156,00 PDF
ODZ-172 anti-Borrelia recom. IgG+VlsE (CSF) 96 wells 172,00 PDF
ODZ-173 anti-Borrelia recom. IgM (CSF) 96 wells 172,00 PDF
  • All prices are in EURO excl. VAT and shipping. Only available in selected countries.

LIA-VIDITEST Borrelia spp.

Order# Description Amount Price Data Sheet
ODZ-316 anti-Borrelia IgG 16 wells 288,00 PDF
ODZ-317 anti-Borrelia IgM 16 wells 288,00 PDF
  • All prices are in EURO excl. VAT and shipping. Only available in selected countries.