Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology

Products

Antigens for Cellular Immunity Testing

Antigens for Cellular Immunity Testing

Blood Cells

Blood Cells

Features

  • Monitoring of virus-specific cellular immunity in patients with high risk of severe infection (transplanted patients, patients with recurrent infections, patients treated with immunotherapy)
  • Individuals before or after vaccination against VZV
  • Ready to use or concentrated antigen

Description

  • Cellular immunity (CI) plays a dominant role in host control of herpesvirus infection. Its impairment may result in the development of chronic recurrent forms of the infection with poor prognosis for the patient. Confirming the virus-specific cellular immunity status is an important issue, especially for patients who are treated with immunosuppressive drugs, e.g., after transplantations or in the course of cancer therapies. It also is beneficial for scheduling vaccinations or immunotherapies, and for monitoring of their efficacy.

  • Native antigens CMV, VZV, HSV-1, HSV-2-CI are intended for virus-specific T- lymphocytes stimulation in tests of adoptive cellular immunity. They are dissolved in lymphocyte cultivation medium in working concentration and then lyophilized. The antigens are dissolved in sterile distilled water before the test and then patient´s leukocytes can be directly added and cultivated.
  • Native CMV, VZV, HSV-1 and HSV-2 antigens – conc. are native lyophilized antigens in concentrated form (0.1 mg).
  • Short time cultivation of virus-specific lymphocytes with the antigen results in the production of cytokines (interferon γ, TNFα, interleukin 2 and others) that can be measured in immunoenzymatic tests, i.e. cytokine release assay (ELISA, ELISPOT) or directly in the cells after staining with a monoclonal antibody (intracellular cytokine staining assay, ICS) using a fluorescence activated cell sorter.

ORDER INFORMATION

  • For shipping and storage information please click on Order#.
Order# Description Amount Price Data Sheet
ODZ-264 CMV - CI combi r.t.u. 1ml 91,00 PDF
ODZ-289 VZV - CI combi r.t.u. 1ml 91,00 PDF
ODZ-314 HSV-1 - CI nativ r.t.u. 1ml 6,40 PDF
ODZ-315 HSV-2 - CI nativ r.t.u. 1ml 6,40 PDF
ODZ-319/05 CMV - CI nativ konc. 0,5 mg 118,70 PDF
ODZ-320 VZV - CI nativ konc 0,1 mg 80,70 PDF
ODZ-321 HSV-1 - CI nativ konc. 0,1 mg 59,20 PDF
ODZ-322 HSV-2 - CI nativ konc. 0,1 mg 59,20 PDF
ODZ-365 Control - CI r.t.u. (for CMV, VZV) on request PDF
ODZ-366 Control - CI r.t.u. (for HSV-1, HSV-2) on request PDF
  • All prices are in EURO excl. VAT and shipping. Only available in selected countries.