Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology

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Herpes simplex Virus – HSV Assay Kits

ELISA-VIDITEST and IF-VIDITEST anti-HSV1+2 Kits

Features

  • Simultaneous detection of anti-HSV1 and anti-HSV2 antibodies
  • Qualitative ELISA for IgG screening and quantitative version for determination of antibody concentration
  • ELISA-VIDITEST anti-HSV1+2 IgM contains RF-sorbent for elimination of interfering IgG antibodies
  • IF assays available for confirmation of the results
  • High sensitivity/specificity verified in diagnostic evaluation study

Description

  • ELISA-VIDITEST and IF-VIDITEST anti-HSV1+2 kits are intended for in vitro diagnosis of HSV type 1 or 2 associated diseases, i.e. herpes labialis, herpes genitalis, herpesvirus gingivostomatitis, keratoconjunctivitis and herpesvirus-induced neurological complications (encephalitis, meningitis, inflammatory mono- and polyneuropathies). The diagnostic kit can also be utilized for differential diagnosis of neuroinfections, infections of eye and skin and exanthematous diseases. The test does not distinguish between HSV1 and HSV2.

  • Primary infections with herpes simplex virus type 1 or 2 are usually asymptomatic, or they reveal as non-specific symptoms such as pharyngitis, specific gingivostomatitis, and oral or genital cutaneous and mucosal lesions. After primo infection the virus persists in organism in a latent state and may be reactivated at any time, usually after some kind of a triggering event. Reactivation of the latent virus is associated with appearance of herpetic lesions at the site of virus entry.

  • An infant being delivered through a birth canal carrying active lesions may develop a serious infection involving the central nervous system (herpetic encephalitis or meningitis), the mouth, eyes (keratoconjuctivitis), or skin (generalized skin rash). The virus may cause severe complications in patients suffering from either inherited or acquired immune deficiency. Infection with HSV (especially with HSV–2) is a risk factor for HIV infection.
  • The detection of class IgG HSV antibodies may be used to determine the immune status of the patient using only a single serum sample or to support diagnosis of HSV primo infection through analysis of paired sera collected 1-2 weeks apart. The detection of IgM antibodies serves as an evidence of primary active infection. However, low levels of IgM can also be detected upon virus reactivation in a latently infected host. Serum IgA antibodies to HSV also reflects active infection, either primo infection or reactivation.

Overview on HSV assay kits

ELISA-VIDITEST RUO
Order # Product Method Evaluation No. of tests Sample Sensitivity/ Specificity
ODZ-169 anti-HSV1+2 IgG ELISA semiquant. 96 serum 98.8% / 97%
ODZ-234 anti-HSV1+2 IgM ELISA semiquant. 96 serum 96.3% / 100%
LIA-VIDITEST RUO
ODZ-059 anti-HSV IFA semiquant. 10x8 serum -

ORDER INFORMATION

  • For shipping and storage information please click on Order#.
Order# Description Amount Price Data Sheet
ODZ-169 anti-HSV1+2 IgG 96 wells 144,00 PDF
ODZ-234 anti-HSV1+2 IgM 96 wells 144,00 PDF
ODZ-059 anti-HSV 80 wells 129,80 PDF
  • All prices are in EURO excl. VAT and shipping. Only available in selected countries.