Innovative Tools for Molecular and Cell Biology

Innovative Tools for Molecular and Cell Biology


PrimeSurface® 3D Culture Spheroid Plates

Form Uniform Spheroids with Ultra-Low Attachment Plates

Time-Lapse Imaging of Human iPS Cells Spheroid (Embryoid Body) Formation


  • The various well bottom shapes of ULA plates provide options for optimum spheroid growth for different cell types. Even though the U bottom plates are most widely used, the V bottom and M (spindle) bottom wells would be a preferred choice for some cell types, especially when developing tight spheroids
  • Uniform single spheroid formation in each well
  • Stable, non-cytotoxic and non-cell adhesion surface
  • Easy handling, compatible with liquid robotic system
  • Sterilized individual packaging


  • PrimeSurface cultureware are ultra low attachment (ULA) dishes and plates that promote scaffold free, self assembly of spheroid formation. The plates are pre-coated with unique ultra hydrophilic polymer that enables spontaneous spheroid formation of uniform size and shape. The ULA plates have high optical clarity making them highly suitable for bright field imaging and confocal microscopy. In addition to the widely used 96 well U bottom plate, 96 well plates are also available in V and M bottom, giving scientist a choice to form tighter spheroids that are needed for specific cell types. For high throughput screening (HTS) needs, 384 well plates are available in clear and white.


  • Stem Cell Research:
  • • Differentiation induction of ES, iPS and mesenchymal stem cells from embryoid body formation

  • Drug Screening Research & Development:
  • • Three dimension spheroid models are more physiologically relevant than two dimension monolayer model
  • • Grow uniform spheroids and screen for drug response in 96 and 384 well plates
  • • 384 white plates are suitable for chemiluminescence assays screening

  • Compatible with Brightfield and Fluorescence Imaging Systems:
  • • Celigo® by Nexcelom
  • • Spheroid applications on IncuCyte® by Sartorius
  • • Cytation 5 Biotek

  • 3D Spheroid Applications Using Ultra Low Attachment (ULA) Plates:
  • Hepatic 3D Spheroid Models for the detection and study of compounds with cholestatic liabilities
  • Growth Inhibition of 3D Tumor Spheres

  • Tissue Engineering, Regenerative Medicine and More
  • • Please see corresponding S-BIO product page.


  • For shipping and storage information please click on Order#.
Order# Description Amount Price Data Sheet
MS-9035XZ PrimeSurface 35mm dish 50 117,00 PDF
MS-9060XZ PrimeSurface 60mm dish 100 520,00 PDF
MS-9090XZ PrimeSurface 90mm dish 50 487,50 PDF
MS-9024XZ PrimeSurface plate 24F 10 156,00 PDF
MS-9384UZ PrimeSurface 384U plate 20 650,00 PDF
MS-9384WZ PrimeSurface 384U White plate 20 812,50 PDF
MS-9096UZ PrimeSurface 96U plate 20 390,00 PDF
MS-9096WZ PrimeSurface 96U White plate 20 520,00 PDF
MS-9096VZ PrimeSurface 96V plate 20 650,00 PDF
MS-9096MZ PrimeSurface 96M plate 20 520,00 PDF
  • All prices are in EURO excl. VAT and shipping. Only available in selected countries.


  • Application Examples in Stem Cell Research (PDF)
  • Stem Cell Spheroid Formation with PrimeSurface (PDF)
  • PrimeSurface Anticancer Drug Screening by: Spheroid Cell Culture (PDF)
  • PrimeSurface Flyer for Drug Screening (PDF)
  • PrimeSurface 96 Slit-Well Plate (PDF)