|Description:||Modified Nucleoside-5′-Triphosphates. Base modified NTPs have been widely used for synthesis of modified mRNA to improve stability and reduce immunogenicity. ABP Biosciences offers a list of key base modified NTPs for mRNA synthesis. 5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of innate immune receptors with in vitro transcribed RNA. 5-Methyl-CTP, as well as Pseudo-UTP and N1-Methylpseudo-UTP, have been shown to reduce innate immune stimulation in culture and in vivo while enhancing translation in recent publications.|
|Unit Size:||10 µL|
|More information:||Go to webpage|
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