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anti-EBNA-1 EBV IgG ELISA (semiquant., quant.)

anti-EBNA-1 EBV IgG ELISA (semiquant., quant.)
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Description: Herpesviruses: Epstein-Barr Virus – EBV: ELISA-VIDITEST anti-EBV and IF-VIDITEST anti-EBV kits are intended for the diagnosis of EBV-associated diseases, i.e. infectious mononucleosis, chronic active EBV infection, EBV-related lymphoproliferative disorders and nasopharyngeal carcinoma. The tests can also contribute to laboratory examination of immune deficiency syndromes, chronic fatigue syndrome and other conditions when reactivation of latent EBV infection is common. Markers of EBV infection: Viral capsid antigen – VCA: structural protein or protein complex, the compound of the viral capsid • EB-viral nuclear antigen 1 – EBNA-1: nonstructural nuclear protein, present in latently infected cells • Early antigen – EA: nonstructural protein or protein complex, synthetized in early phase of viral replication cycle. Based on the structure and localization in the infected cells, two components of EA can be distinguished. EA-R (restricted) component is present in distinct regions of cytoplasm and methanol-resistant EA-D (diffuse) component is dispersed both in the cytoplasm and in the nucleus. Kits for the Detection of Antibodies to EBV Nuclear Antigen – EBNA-1: In acute phase of primary infection IgM antibody is present, while IgG antibody response is delayed. Absence of IgG anti-EBNA with concomitant presence of IgG and IgM anti-VCA is a diagnostic marker of infectious mononucleosis. Long term absence of IgG anti-EBNA-1 antibody may indicate immune deficiency. CE-IVD certified.
Order #: ODZ-001
Unit Size: 96 wells
Supplier: VIDIA
Shipping: Blue Ice
Storage: 4 °C
Subcategory: Infectious Serology
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