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Apilimod (PIKfyve inhibitor)

Apilimod (PIKfyve inhibitor)
Description: Apilimod inhibits the kinase PIKfyve which phosphorylates PI(3)P to PI(3,5)P2 with an IC50 = 14 nM. PIKfyve has an important role in endosome formation and related pathways. Apilimod also inhibits Interleukin-12 (IL-12) and Interleukin-23 (IL-23) at 1-2 nM levels in cells. Apilimod has recently been shown to inhibit SARS-Cov2 replication in iPSC-derived pneumocyte-like cells and a primary human lung explant model. Apilimod is orally bioavailable and cell-permeable.
Order #: B-0308-1-EC
Unit Size: 5mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: See Manual
Storage: See Manual
Subcategory: Biochemical Reagents
More information: Go to webpage
Datasheet Flyer or Brochure
71.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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