mobitec-globe Innovative Tools for Molecular and Cell Biology

SensoLyte® Blue Glucocerebrosidase (GBA) Assay Kit *Fluorimetric*

item-img
Description: Glucocerebrosidase/GBA (also called acid β-glucosidase, Glucosylceramidase,) is a lysosomal enzyme responsible for the breakdown of glucocerebroside releasing glucose and ceramide. Deficiency of this enzyme due to genetic mutations leads to accumulation of glucocerebroside and development of lysosomal storage disease, known as Gaucher disease (GD). Mutations in the glucocerebrosidase (GBA1) gene are also associated with increased risk for Parkinson disease and related disorders. It has been hypothesized that GBA, when not available to clear out proteins like alpha-synuclein, results in the accumulation of the proteins thereby contributing to Parkinson’s disease. The SensoLyte® Blue Glucocerebrosidase (GBA) Assay Kit detects GBA activity by using a most common fluorogenic substrate, MUGlc, for measurement of GBA activity. In presence of GBA the colorless substrate is hydrolyzed into 4-methylumbelliferone (4MU), and after addition of stop solution a bright blue fluorescence can be monitored at excitation/emission = 365nm/445nm nm.
Order #: AS-72258
Unit Size: 1 kit
Supplier: AnaSpec
restrictions: Only available in Germany and selected European countries.
shipping: Dry Ice
Product Subcategory: Enzyme Assays
storage: Component C at -80 °C, all other components at -20 °C
More information: Go to webpage
Datasheet
457.00 € *

*All prices are in € excl. VAT and shipping. Payment terms are 30 days net.

Delivery time approx. 8 – 10 days

    How To Order

    Orders can be placed by phone, fax, and e-mail. Ordering via our online shop will be possible soon. Currently you can use the shop for convenient product selection and to request an offer immediately.

    After placing your order, you will receive an order confirmation via e-mail within 2 working days. If you do not receive this e-mail, please contact us by phone. Thank you!

    Technical Service - Product Information
Viewed

*All prices in € excl. VAT and shipping