|Description:||Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis,Cancer, obesity and related diseases. The SensoLyte® 440 Cathepsin S Assay Kit uses a fluorogenic peptide for measurement ofEnzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin S cleavage, and which can be detected with excitation at 354 nm and emission at 442 nm. The kit contains: , AMC based fluorogenic substrate (Ex/Em=354 nm/442 nm upon cleavage) , Assay buffer , Human spleen Cathepsin S , Inhibitor , Fluorescence reference standard for calibration , A detailed protocol|
|Unit Size:||1 kit|
|Restrictions:||Only available in Germany and selected European countries.|
|Storage:||Component C at -80 °C, all other components at -20 °C|
|More information:||Go to webpage|
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Delivery time approx. 8 - 10 working days
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