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SensoLyte® 520 Deubiquitination Assay Kit Fluorimetric - 1 kit

SensoLyte® 520 Deubiquitination Assay Kit Fluorimetric - 1 kit
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Description: Deubiquitinating enzymes (DUBs) are proteases that reverse ubiquitin modifications and can rescue a protein from proteasomal degradation. DUBs specifically cleave ubiquitin-linked molecules downstream of the terminal carbonyl of the last residue of ubiquitin (Gly76). They are classified in five families. Well-defined families include ubiquitin carboxyl-terminal hydrolases (UCH) and ubiquitin-processing proteases (UBP). DUBs act as regulators of diverse cellular processes, such as development, growth and DNA repair. They have become actively studied molecular targets for drug discovery since they are implicated in the pathogenesis of many human diseases. The SensoLyte® 520 Deubiquitination Assay Kit provides a convenient assay for the screening of enzyme inhibitors and activators or for continuous assay of deubiquitination activity through the use of a fluorogenic peptide substrate. Upon the cleavage by a deubiquitin protease, this substrate generates the green fluorophore that can be detected at excitation/emission=490/520 nm.
Order #: AS-72203
Unit Size: 1 kit
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: Dry Ice
Storage: Store component C at -80°C. Store all other components at -20°C. Component D can be stored at room temperature for convenience. Protect components A and B from light and moisture.
Subcategory: Enzyme Assay Kits
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Datasheet Flyer or Brochure
435.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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