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SensoLyte® 520 Meprin a Activity Assay Kit Fluorimetric - 1 kit

SensoLyte® 520 Meprin a Activity Assay Kit Fluorimetric - 1 kit
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Description: Meprin α is a zinc endopeptidase of the astacin family and the metzincin superfamily. Meprin α can cleave extracellular matrix proteins (pro-collagen I, fibronectin, osteopontin , SPARC), growth factors (VEGF-A, CTGF) and proteinases (MMP-1). Evidence has suggested that Meprin α is associated with cancer proliferation, cancer migration and invasion. The FRET substrate included in SensoLyte® 520 Meprin α Activity Assay Kit was designed to detect Meprin α activity and reduce the cross reactivity with Meprin β, ADAM10, β-secretase, BACE-2, ECEs and TACE. This assay kit can be used to detect enzyme activity in purified enzyme preparations and compound screening. Active Meprin α cleaves the FRET substrate, resulting in an increase of 5-FAM fluorescence, monitored at excitation/emission = 490 nm/520 nm. The long wavelength fluorescence of 5-FAM is also less interfered by the autofluorescence of components in biological samples and test compounds. This assay can detect as low as 0.1 ng/mL active Meprin α.
Order #: AS-72253
Unit Size: 1 kit
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: Dry Ice
Storage: Store component C at -80°C. Store all other components at -20°C. Protect components A and B from light and moisture. Component F can be stored at room temperature for convenience.
Subcategory: Enzyme Assay Kits
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552.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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