|Description:||SMA Copolymer 3:1 for Nanodiscs ׀ Styrene - maleic acid (SMA) copolymers are broadly used for function and structure studies of membrane proteins. The significant advantages of using SMA copolymers include (1) generating a detergent-free system and (2) forming bilayer nanodiscs with phospholipids. Application of SMA copolymers opens an avenue of membrane protein extraction from cell membranes and proteoliposomes in the absence of detergent. The extracted membrane proteins are stabilized in the nanodiscs that mimic the bilayer structure of lipids in nature. The membrane proteins in nanodiscs can be purified and employed in biochemical, biophysical and biological experiments. For example, the nanodiscs can be used for structure studies of membrane proteins by electronic microscopy (EM). Typically SMA copolymers 2:1 forms nanodiscs in a size about 30 nm while SMA copolymers 3:1 forms nanodiscs in a size about 10 nm. The ideal pH for nanodisc formation is between pH 7.0 – 8.0. This product includes 10 ml of 5% Styrene - Maleic Acid Copolymer 3:1 in 0.1 M Tris-HCl, pH 7.6.|
|Unit Size:||10 ml|
|Shipping:||Blue Ice (4°C)|
|More information:||Go to webpage|
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
- Phone: +49 (0)551 707 22 70
- E-mail: firstname.lastname@example.org
How To Order
Orders can be placed by phone, fax, e-mail, or via our online shop:
After placing your order, you will receive an order confirmation via e-mail within 2 working days. If you do not receive this e-mail, please contact us by phone. Thank you! More information regarding our ordering process can be found here.