mobitec-globe Innovative Tools for Molecular and Cell Biology

390 MMP Substrate 13, NFF-3 - 1 mg

390 MMP Substrate 13, NFF-3 - 1 mg
Usage: hover your mouse-pointer anywhere on the image above to see an enlarged portion of the image. You can also just click the image to see the original-sized version.
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense. NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.
Order #: AS-27114
Unit Size: 1 mg
Supplier: AnaSpec
Restrictions: Only available in Germany and selected European countries.
Shipping: RT
Storage: - 20 °C Darkness
Subcategory: Peptides
More information: Go to webpage
Datasheet Flyer or Brochure
Add to request list
    Technical Service - Product Information

    MoBiTec is now part of BIOZOL

    All products can now be ordered via BIOZOL. For price information please use the Add to request list button or visit the BIOZOL webpage.