|Description:||Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.|
|Unit Size:||0.5 mg|
|Restrictions:||Only available in Germany and selected European countries.|
|Storage:||- 20 °C|
|More information:||Go to webpage|
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