Antimicrobial Peptides Represent a Promising Therapeutic Approach in the Post-Antibiotics Era
Antimicrobial peptides (AMPs), also referred to as host defense peptides, are short peptides found in a wide variety of life forms from microorganisms to humans. Many AMPs exhibit an extraordinarily broad range of antimicrobial activity covering both Gram-positive and Gram-negative bacteria as well as fungi, enveloped viruses, and unicellular protozoa. AMPs or their optimized derivatives
- can be used as broad-spectrum antibiotics
- display a rapid killing ability
- are effective against multi-drug-resistant bacteria
- inhibit biofilm formation or reduce/eradicate mature biofilms
- show a complex, often multimodal antimicrobial action which makes it difficult for microbes to develop durable resistance mechanisms
AnaSpec offers a comprehensive range of AMPs, including inhibitors of biofilms, mammalian defensins, cathelicidins, magainins, etc:
Diverse Antimicrobial Peptides
- CAP-18 Product Details: AS-61307
- SMAP-18 Product Details: AS-65595
- BMAP-18 Product Details: AS-65597
- BMAP-27 Product Details: AS-65598
- Cecropins A Product Details: AS-24010
- Cecropins B Product Details: AS-24011
- LEAP - 1, Hepcidin, human Product Details: AS-61432
- Apidaecin IB Product Details: AS-62044
- Indolicidin Product Details: AS-60999
- Rev-4 Product Details: AS-65594
- Drosocin Product Details: AS-62600
Biofilm Inhibitors
Mammalian Defensins
- hBD-1, b-Defensin-1, human AS-60740
- hBD-3, b-Defensin 3 (hBD3) Derivative, human (CHRG01) AS-64886
- hBD - 3, β - Defensin - 3, human AS-60741
- HNP - 1, Defensin Human Neutrophil Peptide – 1 AS-60743
- HNP - 2, Defensin Human Neutrophil Peptide – 2 AS-60744
Cathelicidins
- mCRAMP AS-61305
- rCRAMP AS-61306
- CAP-18, rabbit AS-61307
- PMAP-23 AS-65596
- BMAP-18 AS-65597
- BMAP-27 AS-65598
- Indolicidin AS-60999
- Rev-4 AS-65594
- Bactenecin-2A, Bac2A AS-64906
- SMAP-29 AS-61308
- SMAP-18 AS-65595
Magainins