Description: | USP15 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP15 is a positive regulator of oncogenic TGF-β signaling and that USP15 deubiquitinates monoubiquitinated R-SMADs to enhance target gene promoter binding. USP15 also promotes oncogenic TGF-β signaling by opposing SMURF2-mediated ubiquitination of the type I TGF-β receptor, which facilitates receptor stabilization. |
Order #: | UBP-Y9552-100-100 |
Unit Size: | 100 µl |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Wet ice |
Storage: | -20 °C |
Subcategory: | Deubiquitinating Enzymes |
More information: | Go to webpage |
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