RBX1 Rabbit pAb (UBPBio Product Code: Y6252-100)
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| Description: | RBX1 is an essential component of two distinct but structurally related E3 ubiquitin ligase complexes, the SCF complex and the CBC (VHL) complex. RBX1 mediates the neddylation of CUL1, which activates SCF E3 ligase by facilitating the ubiquitin transfer from E2 to substrates. The RING finger domain of RBX1 is required for ubiquitin ligation. Two evolutionarily conserved mammalian RBX family members, RBX1 and RBX2, have been identified. |
| Order #: | UBP-Y6252-100-100 |
| Unit Size: | 100 µl |
| Supplier: | UBPBio |
| Restrictions: | Only available in selected countries. |
| Shipping: | Wet ice |
| Storage: | -20 °C |
| Subcategory: | E3 Ub Ligases |
| More information: | Go to webpage |
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