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Phospho-MDM2-S166 Rabbit pAb (UBPBio Product Code: Y8002-100)

Phospho-MDM2-S166 Rabbit pAb (UBPBio Product Code: Y8002-100)
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Description: MDM2 is an E3 ubiquitin ligase that targets the p53 protein for proteasomal degradation. Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53. Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53.
Order #: UBP-Y8002-100-100
Unit Size: 100 µl
Supplier: UBPBio
Restrictions: Only available in selected countries.
Shipping: Wet ice
Storage: -20 °C
Subcategory: E3 Ub Ligases
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