ASC Rabbit pAb (UBPBio Product Code: Z5752-100)
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| Description: | ASC is an adaptor protein. It's a 22-kDa pro-apoptotic protein containing an N-terminal pyrin domain (PYD) and a C-terminal caspase recruitment domain (CARD). Expression of ASC/TMS1 can be induced by pro-apoptotic/inflammatory stimuli. During apoptosis ASC/TMS1 is re-distributed from the cytosol to the mitochondria and associates with mitochondrial Bax to trigger cytochrome c release and subsequent apoptosis. ASC/TMS1 has also been found to be a critical component of inflammatory signaling where it associates with and activates caspase-1 in response to pro-inflammatory signals. |
| Order #: | UBP-Z5752-100-100 |
| Unit Size: | 100 µl |
| Supplier: | UBPBio |
| Restrictions: | Only available in selected countries. |
| Shipping: | Wet ice |
| Storage: | -20 °C |
| Subcategory: | Inflammasomes |
| More information: | Go to webpage |
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