Description: | IL-18 belongs to the IL-1 family. It's a proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. |
Order #: | UBP-Z5762-100-100 |
Unit Size: | 100 µl |
Supplier: | UBPBio |
Restrictions: | Only available in selected countries. |
Shipping: | Wet ice |
Storage: | -20 °C |
Subcategory: | Inflammasomes |
More information: | Go to webpage |
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