NAE1 Rabbit pAb (UBPBio Product Code: Y3002-100)
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| Description: | NAE1 (APPBP1) is a subunit of the heterodimeric Nedd8 activating enzyme consisting of NAE1 and UBA3. Nedd8 is conjugated onto the catalytic cysteine residue of UBA3 by formation of a thioester bond in an ATP-dependent reaction. The activated Nedd8 is then passed on to UbE2M (an E2) to be attached to a substrate. Nedd8 is mainly conjugated on Cullins to increase the activity of the Cullin-RING E3 Ub ligases. |
| Order #: | UBP-Y3002-100-100 |
| Unit Size: | 100 µl |
| Supplier: | UBPBio |
| Restrictions: | Only available in selected countries. |
| Shipping: | Wet ice |
| Storage: | -20 °C |
| Subcategory: | UbE1 and E1-Like Proteins |
| More information: | Go to webpage |
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