Quinolone-resistant E. coli Gyrase Mutant D87G Assay kit Plus-100 (ProFoldin Product Code: D87G100KE)
| Description: | Antibacterial Drug Target ׀ Quinolone molecules such as ciprofloxacin are commonly used antibiotics that target bacterial DNA topoisomerases. Mutations S83W and D87G in the gyrA subunit of E.coligyrase are proven causing quinolone resistance. Solving the drug resistance problem requires discovery of new molecules that inhibit the mutant topoisomerases. The Quinolone-resistant E. coli Gyrase Mutant DNA Supercoiling Assay Kits are designed to measure the inhibitory activities of molecules against mutant bacterial gyrases. The assays can be used to test new quinolone compounds in drug discovery. This product includes all the reagents for 100 assays of E. coli gyrase DNA supercoiling activity. This product includes 600 ul of 10 x Buffer T2, 405 ul of 10 x relaxed DNA, 20 ul of 1500 x H19 dye, 450 ul of 10 x ATP, 3000 ul of 10 x H19 dilution buffer and 50 ul 100 x E.coli gyrase mutant D87G. |
| Order #: | PFD-D87G100KE |
| Unit Size: | 100 assays |
| Supplier: | ProFoldin |
| Shipping: | Blue Ice (-20°C) |
| Storage: | See Manual |
| Subcategory: | Drug Discovery |
| More information: | Go to webpage |
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