Description: | Antibacterial Drug Target ׀ Resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins and carbapenems are due to hydrolysis of the four-atom ring known as β-lactam by β-lactamases (penicillinase) produced by Gram-negative bacteria. Inhibition of β-lactamases prevents bacterial degradation of beta-lactam antibiotics. ProFoldin’s high throughput assay for β-lactamases is based on binding of the dye with the hydrolyzed β-lactam that generates fluorescence at 535 nm (excitation at 485 nm). The assay can be performed in a 384-well or 96-well plate format for tests of β-lactamase activities and throughput screening of inhibitors against β-lactamases. This product includes 550 ul of 10 x Buffer and 110 ul of 50 x penicillin G and 260 ul of 10 x fluorescence dye. |
Order #: | PFD-LAC100K |
Unit Size: | 100 assays |
Supplier: | ProFoldin |
Shipping: | Blue Ice (-20°C) |
Storage: | See Manual |
Subcategory: | Drug Discovery |
More information: | Go to webpage |
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