Human Mitochondrial RNA Polymerase Assay Kit Plus (ProFoldin Product Code: MRPA100KE)
| Description: | Anticancer Drug Target ׀ The human mitochondrial RNA polymerase (h-mtRNAP or POLRMT) functions as the transcriptase for expression and the primase for replication of mitochondrial DNA. Its malfunction is related to various diseases and aging. Some antiviral nucleoside analogs were reported to cause chronic toxicity and related to inhibition of mitochondrial RNA polymerase activity. The Human Mitochondrial RNA Polymerase Assay is based on measurement of the RNA molecules synthesized by the RNA polymerase using a DNA template and DNTPs. It is fluorescence assay in a 384-well or 96-well plate format. The assay can be used for measurement activities of human mitochondrial RNA polymerase and drug screens against this enzyme. This product includes 400 ul of 10 x Buffer, 33 ul of 100 x DNA template, 33 ul of 100 x Human Mitochondrial RNA Polymerase, 33 ul of 100 x NTP mix, 330 ul of 10 x fluorescence dye. |
| Order #: | PFD-MRPA100KE |
| Unit Size: | 100 assays |
| Supplier: | ProFoldin |
| Shipping: | Blue Ice (-20°C) |
| Storage: | See Manual |
| Subcategory: | Drug Discovery |
| More information: | Go to webpage |
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