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Description: TMPRSS2 in BacMam for controlled expression in live mammalian cells and increased Spike binding. TMPRSS2 is a host serine protease that cleaves the SARS CoV-2 Spike (S) protein to facilitate entry. Host Factors for Viral Entry: Spike protein on SARS-CoV-2 interacts with the ACE2 receptor on the host cell to initiate viral entry, but other host factors are also involved. While ACE2 is necessary, it does not appear to be sufficient for infection. Host cell factors that are reported to work with ACE2 in SARS-COV-2 entry are now available in BacMam vectors. BacMam is a BSL-1 baculovirus that provides safe, efficient and controllable delivery to practically any cell type. Combine with Pseudo SARS-CoV-2 for COVID19 investigation and discovery.
Order #: C1130N-030
Unit Size: 30 ml Kit
Supplier: Montana Molecular
Restrictions: Available in all European countries.
Shipping: Cool Pack
Storage: 4 °C
Subcategory: Host Cell Factors for SARS-CoV-2 Viral Entry
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