Cardiolipin Grip (Echelon Product Code: G-CL01 2.5UG)
| Description: | Cardiolipin Grip (G-CL01) is a recombinant N-terminal GST-tagged cardiolipin binding protein expressed in E. coli. Cardiolipin Grip recognizes multiple species of cardiolipin in a competitive ELISA format on cardiolipin coated plates. Cardiolipin is an important component in prokaryotic and in eukaryotic inner mitochondrial membrane(1). Autoantibodies to CL have been found in patients with anti-phospholipid syndrome and lupus(2 )and disruptions is CL remodeling have been associated with other diseases such as Barth"s syndrome. Storage: -20 °C. Aliquot and freeze if intended for multiple uses. Protein will be stable for at least 6 months from date of shipment. » References 1) Schlame M, Horvath L, Vigh L. "Relationship between lipid saturation and lipid-protein interaction in liver mitochondria modified by catalytic hydrogenation with reference to cardiolipin molecular species." Biochem J 1990;265:79-85. 2. McNeil HP, Simpson RJ, Chesterman CN, Krilis SA. "Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H)." Proc Natl Acad Sci U S A 1990;87:4120-4. 3. Xu Y. Malhotra A. Ren M. Schlame M. (2006)."The enzymatic function of tafazzin".J. Biol. Chem.281(51): 39217"39224. |
| Order #: | ECH-G-CL01-2.5UG |
| Unit Size: | 2.5 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice |
| Storage: | -20 °C or below |
| Subcategory: | Antibodies & Proteins |
| More information: | Go to webpage |
71.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
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