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Fluorescein conjugated Anti-PI(4, 5)P2 IgM (Echelon Product Code: Z-G045 50UG)

Fluorescein conjugated Anti-PI(4, 5)P2 IgM (Echelon Product Code: Z-G045 50UG)
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Description: Purified Anti-PtdIns(4, 5)P2 monoclonal antibody conjugated with fluorescein. Subclass: IgM Source: Mouse Applications: ELISA, Immunofluorescence Concentration: 0.5 - 1 mg/mL depending on lot number. Please see lot specific TDS. Product Background: Phosphoinositides (PIP(n)s) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4, 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3. Storage Protect from light. 2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times See more details on Bioz; Publications See more details on Bioz; Publications See more details on Bioz; 1) Antony, P., K. Hoek, et al. (2007). µMicro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations." Biol Proced Online 9: 73-83. 2) Heuvingh, J., M. Franco, et al. (2007). "ARF1-mediated actin polymerization produces movement of artificial vesicles." Proc Natl Acad Sci U S A 104(43): 16928-33.
Order #: ECH-Z-G045-50UG
Unit Size: 50 ug
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Dry Ice
Storage: -20 °C or below
Subcategory: Antibodies & Proteins
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