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Pan-Akt VHH Antibody (Echelon Product Code: Z-N001 10UG)

Pan-Akt VHH Antibody (Echelon Product Code: Z-N001 10UG)
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Description: Recombinant anti-Akt Nanobody, Clone # Nb10, COOH-terminal HA tag. Type: VHH single domain Source: E. coli Applications: ELISA, Immunoprecipitation, Pull down Clonality:Monoclonal Background: Pan-Akt VHH Antibody was produced in a llama with a recombinant full length Akt then cloned for recombinant production in E. coli cells. Akt kinases are three highly homologous (Akt 1, 2, 3) isoforms of serine/threonine kinases. Akt, also known as protein kinase b (PKB) is frequently over-activated in cancer and considered as a therapeutic target. However, most small molecule inhibitors lack sufficient specificity and to date there are no effective isoform-specific inhibitors available. Recombinant anti-Akt Nanobody 10 was developed by Gulliver Biomed. Storage Store at -20°C upon arrival. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles. Publications 1) Merckaert, T. et al. (2020). Development and characterization of protein kinase B/AKT isoform-specific nanobodies. PLoS One. 15:e0240554. 2) Merckaert, T. et al. (2021). An AKT2-specific nanobody that targets the hydrophobic motif induces cell cycle arrest, autophagy and loss of focal adhesions in MDA-MB-231 cells. Biomed Pharmacother. 133:111055.
Order #: ECH-Z-N001-10UG
Unit Size: 10 ug
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Dry Ice
Storage: -20 °C or below
Subcategory: Antibodies & Proteins
More information: Go to webpage
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132.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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