Focal Adhesion Kinase VHH Antibody (Echelon Product Code: Z-N004 10UG)
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| Description: | Recombinant anti-Focal Adhesion Kinase Nanobody, Clone # Nb54, COOH-terminal HA tag. Type: VHH single domain Source: (E. Coli) Applications: ELISA, Immunoprecipitation, Pull down Clonality:Monoclonal Background: Focal Adhesion Kinase VHH Antibody was produced in a llama with a protein fragment encompassing mouse FAK amino acids 750-1053 then cloned for recombinant production in (E. Coli). FAK is a cytosolic tyrosine kinase of 125 kDa that concentrates in focal adhesions. It contains FERM (4.1 protein, Ezrin, Radixin, Moesin) and kinase domains that form an autoinhibitory association and a FAT (focal adhesion targeting domain) domain that localizes it to focal adhesions. FAK promotes cell migration by activating a signaling pathway that induces turnover of cell contacts with the underlying matrix. Recombinant anti-Focal Adhesion Kinase Nanobody 54 was developed by Gulliver Biomed. Storage Store at -20°C upon arrival. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles. Publications 1) Van Audenhove I, Debeuf N, Boucherie C, Gettemans J. (2015) Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells. Biochim Biophys Acta; 1853(5):940-952. |
| Order #: | ECH-Z-N004-10UG |
| Unit Size: | 10 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice |
| Storage: | -20 °C or below |
| Subcategory: | Antibodies & Proteins |
| More information: | Go to webpage |
132.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
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