Tensin 4 VHH Antibody (Echelon Product Code: Z-N010 50UG)
Usage: hover your mouse-pointer anywhere on the image above to see an enlarged portion of the image. You can also just click the image to see the original-sized version.
| Description: | Recombinant anti-Tensin 4 Nanobody, Clone # Nb12, COOH-terminal HA tag. Type: VHH single domain Source: (E. Coli) Applications: ELISA, Immunoprecipitation, Pull down Clonality:Monoclonal Background: Tensin 4 VHH Antibody was produced in an llama with a fragment of Tensin4 encompassing residues 428-714 then cloned for recombinant production in (E. Coli). Tensin, aka TNS4 or CTEN, is a component of the cytoskeleton and localizes close to or at focal adhesions, connecting the cytoplasmic tail of integrins with actin filaments. It contains a C-terminal SH2 and PTB (phosphotyrosine binding domain) and binds tyrosine-phosphorylated proteins that assemble into signaling complexes at focal adhesions. Its expression has been reported to be down regulated in prostate cancer, but upregulated in lung and breast cancer. Recombinant anti-Tensin 4 Nanobody 12 was developed by Gulliver Biomed. Storage Store at -20°C upon arrival. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles. Publications 1) Bertier L, et al. (2018) Nanobodies targeting cortactin proline rich, helical, and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells. Biomed Pharmacother; 102:230-241 2) Van Audenhove I, et al. (2016) Nanobodies as versatile tools to understand, diagnose, visualize, and treat cancer. EBioMedicine; 8:40-48 |
| Order #: | ECH-Z-N010-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice |
| Storage: | -20 °C or below |
| Subcategory: | Antibodies & Proteins |
| More information: | Go to webpage |
299.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
- Phone: +49 (0)89 3799666-6
- Fax: +49 (0)89 3799666-99
- E-mail: order@biozol.de
- Online Shop: www.mobitec.com
- Phone: +49 (0)89 3799666-6
- E-mail: info@biozol.de
How To Order
Orders can be placed by phone, fax, e-mail, or via our online shop:
MoBiTec is now part of BIOZOL
All orders and requests placed via the online shop on www.mobitec.com are processed by BIOZOL Diagnostica Vertrieb GmbH.
You will receive an order confirmation by fax or e-mail. More information regarding the ordering process can be found here.
Technical Service - Product Information
Viewed