Purified Anti-PtdIns(4)P IgM (Echelon Product Code: Z-P004 50UG)
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| Description: | Purified Anti-PtdIns(4)P monoclonal antibody.Subclass: IgMSource: MouseApplications: ELISA Immunofluorescence Fluorescence Polarization Protein-Lipid Overlay (PIP Strip)Product Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Storage2-8 °C for up to 30 days -20 °C for greater than 30 days. Do not freeze thaw multiple times. Powered by Bioz See more details on BiozFeatured in Publications1) Weber S. S. C. Ragaz et al. (2006). "Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole." PLoS Pathog 2(5): e46.2) Blagoveshchenskaya A. F. Y. Cheong et al. (2008). "Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1." J Cell Biol 180(4): 803-12.3) Cheong F. Y. V. Sharma et al. (2010). "Spatial Regulation of Golgi Phosphatidylinositol-4-Phosphate is Required for Enzyme Localization and Glycosylation Fidelity." Traffic 11(9): 1180-1190.4) Bojjireddy N. J. Botyanszki et al. "Pharmacological and Genetic Targeting of the PI4KA Enzyme Reveals Its Important Role in Maintaining Plasma Membrane Phosphatidylinositol 4-Phosphate and Phosphatidylinositol 4 5-Bisphosphate Levels." Journal of Biological Chemistry 289(9): 6120-6132.Product keywords: PtdIns(4)P anti-PI(4)P PI4P IgM |
| Order #: | ECH-Z-P004-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice |
| Storage: | -20 °C or below |
| Subcategory: | Antibodies & Proteins |
| More information: | Go to webpage |
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