Vac14 Antibody polyclonal (Echelon Product Code: Z-RV14 50UG)
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| Description: | Vac14 also known as ArPIKfyve is a scaffold protein that functions in a complex with PIKfyve and Sac3 (FIG4). This complex regulates the synthesis and turnover of phosphatidylinositol 3 5-bisphosphate (PI(3 5)P2) on endosomal membranes. Vac14 forms a pentamer at the membrane to facilitate assembly of the complex and binds a single copy each of PIKFYVE and Sac3. The coordinated lipid kinase and phosphatase activity within the complex maintains homeostasis of PI(3)P and PI(5)P and plays a role in the fusion and transport of endosomes.Z-RV14 Vac14 antibody has been validated for WB IP and ICC and has been shown to recognize human and mouse/rat isoforms. The antibody was generated from a fusion protein with amino acids 523 to 782 of human Vac14. |
| Order #: | ECH-Z-RV14-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice |
| Storage: | -80 °C or below |
| Subcategory: | Antibodies & Proteins |
| More information: | Go to webpage |
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