Sphingosine Kinase Inhibitor (SKI-II) (Echelon Product Code: B-0024 10MG)
| Description: | 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC(50) = 0.5 µM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKC" at concentrations up to 60 µM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. |
| Order #: | ECH-B-0024-10MG |
| Unit Size: | 10 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | 4-8 °C |
| Subcategory: | Biochemical Reagents |
| More information: | Go to webpage |
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