2-Acetyl-5-tetrahydroxybutyl imidazole (THI) (Echelon Product Code: B-0031 5MG)
| Description: | THI is a trace component present in the industrially produced food colorant caramel color III. It acts as an immunosuppressant by inhibiting the enzyme sphingosine 1-phosphate lyase (S1PL) which fragments S1P to hexadecenal and phosphoethanolamine. Administration of THI in drinking water to mice (50 "g/mL) resulted in decreased S1PL activity, increased S1P levels in lymphoid tissues and reduced egress of CD4+ and CD8+ T cells (lymphopenia). |
| Order #: | ECH-B-0031-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | 4-8 °C |
| Subcategory: | Biochemical Reagents |
| More information: | Go to webpage |
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