Description: | CYM50308 is a potent and selective S1P4 receptor agonist with EC50 of 37.7 nM - 79.1nM. It is inactive against the S1P1, S1P2, and S1P3 receptors up to 25 µM, and the S1P5 receptor up to 2.1 µM. » References 1) Urbano et al. Discovery, synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z, 5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2- (alkylimino)thiazolidin-4-one chemotype, Bioorganic & Medicinal Chemistry Letters, 2011, 6739-6745. 2) Guerrero et al. Identification of a novel agonist of the sphingosine 1-phosphate receptor 4 (S1P4), Probe Reports from the NIH Molecular Libraries Program. http://www.ncbi.nlm.nih.gov/books/NBK143556/; |
Order #: | ECH-B-0060-50MG |
Unit Size: | 50 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | 4-8 °C |
Subcategory: | Biochemical Reagents |
More information: | Go to webpage |
734.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
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