Description: | 5-(2, 2-Difluoro-benzo[1, 3]dioxol-5-ylmethylene)-thiazolidine-2, 4-dione (AS604850) is an inhibitor of PI 3-K" with an IC(50) = 250 nM. AS604850 is selective for the "-isoform (IC(50): PI 3-K" = 4.5 µM, PI 3-K", PI 3-K" 20 µM) and shows no notable activity against a wide array of protein kinases at 1 µM. » References; 1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine, 2005, 11, 936-943. |
Order #: | ECH-B-0302-5MG |
Unit Size: | 5 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | 4-8 °C |
Subcategory: | Biochemical Reagents |
More information: | Go to webpage |
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