ZSTK474 (PI3K Inhibitor) (Echelon Product Code: B-0307 100MG)
| Description: | ZSTK474 is a potent inhibitor of all four isoforms of class I PI 3-kinase (" 6.7 nM, " 10.4 nM, " 11.7 nM, " 1.8 nM). It binds to the ATP-binding pocket and is more active and less toxic than LY294002. ZSTK474 shows anti-tumor activity against human xenografts (A549, PC-3, WiDr) in mice by arresting cell growth. In addition, it was able to inhibit osteoclast formation and collagen-induced arthritis in a mouse model. |
| Order #: | ECH-B-0307-100MG |
| Unit Size: | 100 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | -20 °C or below |
| Subcategory: | Biochemical Reagents |
| More information: | Go to webpage |
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