PS48 (PDK1 Activator) (Echelon Product Code: B-0360 5MG)
| Description: | PS48 activates phosphoinositide-dependent protein kinase 1 (PDK1) by binding exclusively to PIF-binding pocket rather than the ATP binding site. » References 1) A. Stroba et al. "3, 5-Diphenylpent-2-enoic Acids as Allosteric Activators of the Protein Kinase PDK1: Structure-Activity Relationships and Thermodynamic Characterization of Binding as Paradigms for PIF-Binding Pocket-Targeting Compounds", J. Med. Chem, 2009, 52 (15), 4683-4693; 2) L.D. Spate, et al. "PS48 can replace bovine serum albumin in pig embryo culture medium, and improve in vitro embryo development by phosphorylating AKT" Molecular Reproduction & Development 2015, DOI: 10.1002/mrd.22474. |
| Order #: | ECH-B-0360-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Room Temperature |
| Storage: | 4-8 °C |
| Subcategory: | Biochemical Reagents |
| More information: | Go to webpage |
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