NeoBeads - PIP Purification System (Echelon Product Code: P-B999 20MG)
| Description: | The NeoBeads - PIP Purification System is useful in biological and chemical applications for purification of lipids. Each milligram of beads will bind at least 1 nmole phosphoinositide. The NeoBeads - PIP Purification System allows for selective purification/immobilization of phosphoinositides from biological samples. Phosphoinositides can be recovered from the beads using fresh 2 M aqueous triethylamine bicarbonate, chloroform, methanol (3:2:6; v/v). See the Technical Data Sheet for protocol and further details. - Quick purification of Phosphoinositides from biological samples - High Binding capacity: greater than 1 nanomole phosphoinositide per mg bead - Reproducable batches: low lot-to-lot variability - Cited in multiple scientific papers over 20+ years describing uses, techniques and protocols. - First commercially available solid-supported neomycin. » References 1) A. Grey, H. Olsson, I.H. Batty, L. Priganica, C.P. Downes: Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphates and selective detection of signaling lipids in cell and tissue extracts. Analytical Biochemistry 313 234-245 (2003). 2)Sbrissa, D., Ikonomov, O. C., Deeb, R., and Shisheva, A., Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells, J Biol Chem, 277, 47276 (2002). 3) Sierra Potchanant, E. A., et al. (2016). "INPP5E preserves genomic stability through regulation of mitosis." Mol Cell Biol 37: e00500-00516. |
| Order #: | ECH-P-B999-20MG |
| Unit Size: | 20 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Gel Ice |
| Storage: | 4-8 °C, Do Not Freeze! |
| Subcategory: | Biochemical Reagents |
| More information: | Go to webpage |
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