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306Oi10 (Echelon Product Code: N-1010 10MG)

306Oi10 (Echelon Product Code: N-1010 10MG)
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Description: 306Oi10 is a biodegradable, branched chain lipidoid developed for RNA delivery in lipid nanoparticles (LNPs). Interestingly, the unbranched analog was 10-fold less effective in delivering luciferase mRNA in mice. The increased potency is thought to be due to increased cone-shaped structure and protonation at endosomal pH resulting in enhanced endosomal escape. 306Oi10 has been used to co-deliver three mRNAs (firefly luciferase, mCherry, and erythropoietin). The LNPs derived from 306Oi10 were not immunogenic or toxic to the liver.
Order #: ECH-N-1010-10MG
Unit Size: 10mg
Supplier: Echelon Biosciences
Restrictions: Available in all European countries, except France & Italy.
Shipping: Gel Ice
Storage: -20°C or below
Subcategory: Lipid Nanoparticles
More information: Go to webpage
Datasheet Flyer or Brochure Product Image
74.00 € *

*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).

Delivery time approx. 8 - 10 working days

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