Description: | Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. cKK-E12 has been used to deliver siRNA in mice, rats, and primates (ED(50) = 0.002, 0.01, & 0.3 mg/kg respectively). It shows low toxicity and is selective for liver parenchymal cells over liver, heart, lung, and kidney endothelial cells. This product is for u research use only /u and u not /u for human use. Additional information can be found here. » References Dong et al. (2014) Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. PNAS Mar 18;111(11):3955-60 |
Order #: | ECH-N-1012-10MG |
Unit Size: | 10 mg |
Supplier: | Echelon Biosciences |
Restrictions: | Available in all European countries, except France & Italy. |
Shipping: | Room Temperature |
Storage: | 4-8 °C |
Subcategory: | Lipid Nanoparticles |
More information: | Go to webpage |
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