BODIPY FL PI(3)P (Echelon Product Code: C-03F6 100UG)
| Description: | BODIPY FL PI(3)P (BODIPY FL Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the green fluorophore, Bodipy(©)-FL at the sn-1 position. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. Excitation/Emission 503/513 nm Storage -20 °C, protect from light 1) Caromile, L. A., A. Oganesian, et al. (2010). "The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion." J Biol Chem 285(14): 10487-96. 2)Rudge, S. A., D. M. Anderson, et al. (2004). "Vacuole size control: regulation of PtdIns(3, 5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3, 5)P2-specific phosphatase." Mol Biol Cell 15(1): 24-36. 3) Oganesian, A., M. Poot, et al. (2003). "Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation." Proc Natl Acad Sci U S A 100(13): 7563-8. |
| Order #: | ECH-C-03F6-100UG |
| Unit Size: | 100 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below, protect from light |
| Subcategory: | Lipids |
| More information: | Go to webpage |
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