BODIPY TMR PI(4, 5)P2 (Echelon Product Code: C-45M6 50UG)
| Description: | BODIPY TMR PI(4, 5)P2 (BODIPY TMR Phosphatidylinositol 4, 5-bisphosphate) is a water soluble analog of PI(4, 5)P2 (PIP2) labeled with the orange fluorophore, Bodipy(©)-TMR, at the sn-1 position. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4, 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3, 4, 5)P3. Excitation/Emission 542/574 nm Storage -20 °C, protect from light 1) Cabanos C, Wang M, Han X, Hansen SB (2017) A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Rep 20(6):1287"1294; |
| Order #: | ECH-C-45M6-50UG |
| Unit Size: | 50 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below, protect from light |
| Subcategory: | Lipids |
| More information: | Go to webpage |
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