1-Stearoyl-2-Arachidonoyl-sn-Glycerol (Echelon Product Code: L-0024 5MG)
| Description: | 1-Stearoyl-2-arachidonoyl-(sn)-glycerol is a diacylglycerol (DAG) with polyunsaturated fatty acid arachidonic acid and stearic acid in the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-arachidonoyl-(sn)-glycerol is a diacylglycerol is a potent activator of PKC×ñ, PKC×µ, and PKC×ï and also competitively binds to the Ras activator RasGRP. 1, 2-Diacylglycerols are formed in cells through the hydrolysis of phosphatidylinositol 4, 5-bisphosphate by Phospholipase C. DAGs activate Protein Kinase C (PKC), which is a key regulator of signal transduction, cellular regulation, and tumor promotion. » References 1) Lapetina, E.G., Reep, B., Ganong, B.R. & Bell, R.M., (1985), Exogenous sn-1, 2-diacylglycerols Containing Saturated Fatty Acids Functions as Bioregulators of Protein Kinase C in Human Platelets;", (J. Biol. Chem. )260, 1358-1361. 2) Ganong, B.R., Loomis, C.R., Hannun, Y.A. & Bell, R.M., (1986), Specificity and Mechanism of Protein Kinase C Activation by sn-1, 2-diacylglycerols;", (Proc. Natl. Acad. Sci. USA )83, 1184-1188. |
| Order #: | ECH-L-0024-5MG |
| Unit Size: | 5 mg |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Gel Ice |
| Storage: | -80 °C or below |
| Subcategory: | Lipids |
| More information: | Go to webpage |
101.00 € *
*All prices are net in Euro and do not include applicable taxes, shipping & handling, or other charges (e.g., customs duties).
Delivery time approx. 8 - 10 working days
- Phone: +49 (0)89 3799666-6
- Fax: +49 (0)89 3799666-99
- E-mail: order@biozol.de
- Online Shop: www.mobitec.com
- Phone: +49 (0)89 3799666-6
- E-mail: info@biozol.de
How To Order
Orders can be placed by phone, fax, e-mail, or via our online shop:
MoBiTec is now part of BIOZOL
All orders and requests placed via the online shop on www.mobitec.com are processed by BIOZOL Diagnostica Vertrieb GmbH.
You will receive an order confirmation by fax or e-mail. More information regarding the ordering process can be found here.
Technical Service - Product Information
Viewed