PI(4, 5)P2 diC8 (Echelon Product Code: P-4508 500UG)
| Description: | Phosphatidylinositol 4, 5-bisphosphate diC8 (PI(4, 5)P2 diC8) is a synthetic, purified dioctanoyl PI(4, 5)P2. Phosphoinositides (PIP(n)s) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4, 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K). Alternate Names: D-myo-Phosphatidylinositol 4, 5-bisphosphate, Dioctanoyl Phosphatidylinositol 4, 5-bisphosphate, PtdIns(4, 5)P2 C8, PI(4, 5)P2 C8, or PIP2 1) Jenco, J. M., A. Rawlingson, et al. (1998). "Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins." Biochemistry 37(14): 4901-9. 2) Campbell, R. B., F. Liu, et al. (2003). "Allosteric activation of PTEN phosphatase by phosphatidylinositol 4, 5-bisphosphate." J Biol Chem 278(36): 33617-20. 3) Haider, S., A. I. Tarasov, et al. (2007). "Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis." EMBO J 26(16): 3749. 4) Lewis, A. E., L. Sommer, et al. (2011). "Identification of nuclear phosphatidylinositol 4, 5-bisphosphate-interacting proteins by neomycin extraction." Mol Cell Proteomics 10(2): M110 003376. |
| Order #: | ECH-P-4508-500UG |
| Unit Size: | 500 ug |
| Supplier: | Echelon Biosciences |
| Restrictions: | Available in all European countries, except France & Italy. |
| Shipping: | Dry Ice Or Gel Ice Depending On Destination |
| Storage: | -20 °C or below |
| Subcategory: | Lipids |
| More information: | Go to webpage |
Add to request list
- Phone: +49 (0)89 3799666-6
- E-mail: info@biozol.de
MoBiTec is now part of BIOZOL
All orders and requests placed via the online shop on www.mobitec.com are processed by BIOZOL Diagnostica Vertrieb GmbH.
You will receive an order confirmation by fax or e-mail. More information regarding the ordering process can be found here.
Technical Service - Product Information
Viewed